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Merck
모든 사진(2)

주요 문서

SAB5200110

Sigma-Aldrich

Anti-AQP2 antibody produced in rabbit

1 mg/mL, affinity isolated antibody

동의어(들):

Anti-AQP-CD, Anti-AQP2, Anti-AQPCD, Anti-Aquaporin 2

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous glycerol solution

분자량

antigen predicted mol wt 28.8 kDa

종 반응성

human, mouse, rat

농도

1 mg/mL

기술

indirect immunofluorescence: suitable
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

rat ... Aqp2(25386)

일반 설명

The gene ID of the protein aquaporin-2 (AQP2) is 25386.

특이성

Detects ~28.8 kDa. May detect larger glycosylated bands ~35-50 kDa.

면역원

C-terminal peptide

생화학적/생리학적 작용

Aquaporin 2 (AQP2) takes part in maintaining the water balance in cells. A high concentration of the protein has been observed in rats during hypothyroidism.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

PBS, pH 7..4, 50% glycerol, and 0.09% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Lorena I Sarati et al.
Metabolism: clinical and experimental, 62(9), 1287-1295 (2013-05-28)
Hypothyroid state and aging are associated with impairment in water reabsorption and changes in aquaporin water channel type 2 (AQP2). Nitric oxide (NO) is involved in AQP2 trafficking to the apical plasma membrane in medullary collecting duct cells. The purpose
William J Monis et al.
The Journal of cell biology, 216(7), 2131-2150 (2017-06-04)
Primary cilia perceive the extracellular environment through receptors localized in the ciliary membrane, but mechanisms directing specific proteins to this domain are poorly understood. To address this question, we knocked down proteins potentially important for ciliary membrane targeting and determined
Annette Hus-Citharel et al.
Endocrinology, 155(11), 4483-4493 (2014-08-27)
Apelin receptors (ApelinRs) are expressed along an increasing cortico-medullary gradient in collecting ducts (CDs). We showed here that iv injection of apelin 17 (K17F) in lactating rats characterized by increases in both synthesis and release of arginine vasopressin (AVP) increased
Naohiro Nomura et al.
American journal of physiology. Cell physiology, 307(7), C597-C605 (2014-06-20)
A reduction or loss of plasma membrane aquaporin 2 (AQP2) in kidney principal cells due to defective vasopressin (VP) signaling through the VP receptor causes excessive urine production, i.e., diabetes insipidus. The amount of AQP2 on the plasma membrane is

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