추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 26 kDa
종 반응성
rat, human, mouse
농도
~1 mg/mL
기술
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... LGALS3(3958)
일반 설명
Anti-Galectin 3 Antibody detects endogenous levels of total Galectin 3 protein.
Galectin 3 is a carbohydrate-binding protein. It is abundantly expressed in the extracellular matrix, the cytoplasm and the nucleus. It contains an intrinsically disordered N-terminal domain and a canonical CRD (carbohydrate recognition domain). It is mapped to human chromosome 14q22.
Galectin 3 is a carbohydrate-binding protein. It is abundantly expressed in the extracellular matrix, the cytoplasm and the nucleus. It contains an intrinsically disordered N-terminal domain and a canonical CRD (carbohydrate recognition domain). It is mapped to human chromosome 14q22.
면역원
The antiserum was produced against synthesized peptide derived from human Galectin 3.
Immunogen Range: 141-190
Immunogen Range: 141-190
생화학적/생리학적 작용
Galectin 3 controls cell activation, migration, adhesion and signaling. It plays a role in cancer progression after it is initiated. Expression of galectin-3 regulates apoptosis and development of T-cell. It participates in several physiological and pathological processes like pre-mRNA splicing, neoplastic transformation and immune responses.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
LGALS3 (lectin, galactoside-binding, soluble, 3).
Nangia-Makker P, et al.
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 15(6) (2011)
Ping-Ping Lang et al.
Laboratory investigation; a journal of technical methods and pathology, 100(3), 378-386 (2019-09-19)
Monocyte and adhesion infiltration into the arterial subendothelium are initial steps in hypertension development. The endothelial intercellular adhesion molecule-1 (ICAM-1) has been implicated in the recruitment and adhesion of leukocytes in several cardiac diseases. However, the role of ICAM-1 in
The intrinsically disordered N-terminal domain of galectin-3 dynamically mediates multisite self-association of the protein through fuzzy interactions.
Lin YH, et al.
The Journal of Biological Chemistry, 292(43), 17845-17856 (2017)
Expression of galectin-3 modulates T-cell growth and apoptosis.
Yang RY, et al.
Proceedings of the National Academy of Sciences of the USA, 93(13), 6737-6742 (1996)
József Murányi et al.
International journal of molecular sciences, 20(22) (2019-11-14)
Several promising anti-cancer drug-GnRH (gonadotropin-releasing hormone) conjugates have been developed in the last two decades, although none of them have been approved for clinical use yet. Crizotinib is an effective multi-target kinase inhibitor, approved against anaplastic lymphoma kinase (ALK)- or
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