추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 61 kDa
종 반응성
human, rat, mouse
농도
~1 mg/mL
기술
ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... HSPD1(3329)
일반 설명
Anti-HSP60 antibody detects endogenous levels of total HSP60 protein.
Hsp60 (heat shock protein family D member 1) is a mitochondrial chaperone, located in the endoplasmic reticulum (ER). It is mapped to human chromosome 2q33.1.
면역원
The antiserum was produced against synthesized peptide derived from human HSP60.
Immunogen Range: 511-560
Immunogen Range: 511-560
애플리케이션
Anti-HSP60, C-Terminal antibody has been used in SDS/PAGE and western blot analysis.
생화학적/생리학적 작용
Hsp60 (heat shock protein family D member 1) helps to gather proteins that are imported into mitochondrial matrix. Overexpression of Hsp60 results in Behcet′s Disease (BD),Crohn′s disease, juvenile dermatomyositis (JDM), and juvenile idiopathic arthritis (JIA) and rheumatoid arthritis (RA).
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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이미 열람한 고객
OPA1 functionally interacts with MIC60 but is dispensable for crista junction formation
Barrera M, et al.
Febs Letters, 590(19), 3309-3322 (2016)
Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria
Cheng MY, et al.
Nature, 337(6208), 620-625 (1989)
HSPD1 (heat shock 60kDa protein 1)
Faried A and Faried L S
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2007)
HSP60: a double edge sword in autoimmunity
Landstein D, et al.
Oncotarget, 6(32), 32299-32300 (2015)
Anti-breast tumor activity of Eclipta extract in-vitro and in-vivo: novel evidence of endoplasmic reticulum specific localization of Hsp60 during apoptosis
Arya RK, et al.
Scientific Reports (2015)
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