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Merck
모든 사진(2)

주요 문서

SAB4501310

Sigma-Aldrich

Anti-GR antibody produced in rabbit

affinity isolated antibody

동의어(들):

GCR, GRL, GRL1, NR3C1, glucocorticoid receptor

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen 85 kDa

종 반응성

human, rat, mouse

농도

~1 mg/mL

기술

ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... GCR(2908)

일반 설명

Anti-GR antibody detects endogenous levels of total GR protein.
Glucocorticoid receptor (GR) gene/NR3C1 (nuclear receptor subfamily 3 group C member 1) is located on human chromosome 5q31.

면역원

The antiserum was produced against synthesized peptide derived from human GR.

Immunogen Range: 201-250

애플리케이션

Anti-GR antibody has been used in western blotting.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

생화학적/생리학적 작용

The glucocorticoid receptor (GR) gene/(NR3C1) is associated with asthma. It is required for glucose homeostasis, hyperinsulinemia and increased fat deposition. It also regulates cell differentiation, nervous and immune system functions.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

The Role of Hippocampal NMDA Receptors in Long-Term Emotional Responses following Muscarinic Receptor Activation
Hoeller AA, et al.
PLoS ONE, 11(1), e0147293-e0147293 (2016)
Alexandre A Hoeller et al.
PloS one, 11(1), e0147293-e0147293 (2016-01-23)
Extensive evidence indicates the influence of the cholinergic system on emotional processing. Previous findings provided new insights into the underlying mechanisms of long-term anxiety, showing that rats injected with a single systemic dose of pilocarpine--a muscarinic receptor (mAChR) agonist--displayed persistent
Identification of polymorphisms in the human glucocorticoid receptor gene (NR3C1) in a multi-racial asthma case and control screening panel
Hawkins GA, et al.
Dna Sequence, 15(3), 167-173 (2004)
Structure of the glucocorticoid receptor (NR3C1) gene 5' untranslated region: identification, and tissue distribution of multiple new human exon 1
Turner JD and Muller CP
Journal of Molecular Endocrinology, 35(2), 283-292 (2005)
Glucocorticoid receptor polymorphism in obesity and glucose homeostasis
Majer-Lobodzinska A and Adamiec-Mroczek J
Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University, 26(1), 143-148 (2017)

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