추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 19 kDa
종 반응성
mouse, human
농도
~1 mg/mL
기술
ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... PARK7(11315)
일반 설명
Anti-DJ-1 Antibody detects endogenous levels of total DJ-1 protein.
DJ-1 (protein deglycase)/PARK7 (parkinsonism associated deglycase) is an oncogene, made of 189 amino acids. It is present in several human tissues and is located on chromosome 1p36.
면역원
The antiserum was produced against synthesized peptide derived from human DJ-1.
Immunogen Range: 21-70
Immunogen Range: 21-70
애플리케이션
Anti-DJ-1 antibody has been used in western blotting.
생화학적/생리학적 작용
In lung cancer patients, DJ-1 (protein deglycase) acts as a biomarker for the initial prognosis. It also acts as a serum biomarker for identifying high-risk endometrial cancer.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
DJ-1 is a reliable serum biomarker for discriminating high-risk endometrial cancer
Di Cello A, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(6) (2017)
DJ-1 as a potential biomarker for the early diagnosis in lung cancer patients
Han B, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 39(6) (2017)
Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36
van Duijn CM, et al.
American Journal of Human Genetics, 69(3), 629-634 (2001)
Kuldip D Dave et al.
Neurobiology of disease, 70, 190-203 (2014-06-28)
Recessively inherited loss-of-function mutations in the PTEN-induced putative kinase 1(Pink1), DJ-1 (Park7) and Parkin (Park2) genes are linked to familial cases of early-onset Parkinson's disease (PD). As part of its strategy to provide more tools for the research community, The
Min Sik Choi et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(45), 15123-15131 (2014-11-08)
Emerging evidence suggests that oxidative/nitrosative stress, as occurs during aging, contributes to the pathogenesis of Parkinson's disease (PD). In contrast, detoxification of reactive oxygen species and reactive nitrogen species can protect neurons. DJ-1 has been identified as one of several
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