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Merck
모든 사진(3)

주요 문서

SAB4300492

Sigma-Aldrich

Anti-CDC2 (Ab-15) antibody produced in rabbit

affinity isolated antibody

동의어(들):

Anti-CDC28A antibody produced in rabbit, Anti-CDK1 antibody produced in rabbit, Anti-DKFZp686L20222 antibody produced in rabbit, Anti-MGC111195 antibody produced in rabbit, Anti-cell division cycle 2, G1 to S and G2 to M antibody produced in rabbit

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

~34 kDa

종 반응성

human, rat, mouse

농도

1 mg/mL

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

동형

IgG

면역원 서열

(G-T-Y-G-V)

NCBI 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... CDC2(983)

일반 설명

CDC2/CDK1 (cyclin-dependent kinase 1) belongs to the Ser/Thr protein kinase family. It is located on human chromosome 10q21.

면역원

Peptide sequence around aa. 13-17 (G-T-Y-G-V), according to the protein CDC2.

생화학적/생리학적 작용

CDC2/CDK1 (cyclin-dependent kinase 1) controls various mitotic processes like reorganization of the cytoskeleton, segregation of chromosome, formation and separation of daughter cells. It is essential for the multiplication of mammalian cell. It participates in tumorigenesis.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

표적 설명

Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy
Bieche I, et al.
Molecular Cancer, 10:23 (2011)
Recurrent CDK1 overexpression in laryngeal squamous cell carcinoma
Bednarek K, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 37(8), 11115-11126 (2016)
Identification of Candidate Cyclin-dependent kinase 1 (Cdk1) Substrates in Mitosis by Quantitative Phosphoproteomics
Petrone A, et al.
Molecular and Cellular Proteomics, 15(7), 2448-2461 (2016)

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