추천 제품
생물학적 소스
mouse
Quality Level
결합
unconjugated
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
NTS-11, monoclonal
양식
buffered aqueous solution
종 반응성
rat, human
농도
~1 mg/mL
기술
immunoblotting: 5-10 μg/mL using whole extract of SK-N-SH cells
immunohistochemistry: 10-20 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded rat brain sections
동형
IgG1
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... NTS(4922)
rat ... Nts(299757)
일반 설명
Anti-Neurotensin/NTS antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the NTS-11 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mouse immunized with synthetic peptide. Neurotensin (also known as NTS or NT) is a 13 amino acid brain-gut peptide.
면역원
Synthetic peptide from C-terminal region of human Neurotensin, conjugated to KLH
애플리케이션
Anti-Neurotensin/NTS antibody, Mouse monoclonal has been used in:
- immunoblotting
- immunohistochemistry
- immunofluorescence
생화학적/생리학적 작용
Neurotensin (NTS) functions as a neurotransmitter/neuromodulator in the central nervous system (CNS) and as an endocrine agent in the gastrointestinal (GI) tract. Neurotensin is involved in a variety of physiological processes such as, stress and pain modulation, pathophysiology of drug addiction, schizophrenia, Parkinson disease, depression, locomotion and reward. In the brain, neurotensin modulates dopaminergic transmission in the nigrostriatal and mesocorticolimbic pathways as well as hormone secretion from the anterior pituitary.
물리적 형태
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
G S Katsanos et al.
International journal of immunopathology and pharmacology, 21(2), 255-259 (2008-06-13)
The tridecapeptide neurotensin (NT) acts in the mammalian brain as a primary neurotransmitter or neuromodulator of classical neurotransmitters. Morphological and functional in vitro and in vivo studies have demonstrated the existence of close interactions between NT and dopamine both in
Konstantinos Kalafatakis et al.
Regulatory peptides, 170(1-3), 7-17 (2011-05-10)
Among various hormones, which are synthesized by intestinal cells and influence enteric function, neurotensin (NT) has gained scientific attention the last three decades. This neuropeptide, mainly located in neuronal synaptic vesicles of hypothalamus and in neuroendocrine cells of the small
W Conan Mustain et al.
Current opinion in endocrinology, diabetes, and obesity, 18(1), 75-82 (2010-12-03)
Neurotensin is a 13-amino acid peptide found in the central nervous system central nervous system and the gastrointestinal tract. Since its initial discovery in 1973, neurotensin has been shown to play a role in a wide range of physiologic and
The role of neurotensin as a novel biomarker in the endoscopic screening of high-risk population for developing colorectal neoplasia
Kontovounisios C, et al.
Updates in Surgery, 69(3), 397-397 (2017)
B Mark Evers
Peptides, 27(10), 2424-2433 (2006-08-15)
Neurotensin (NT) is a brain-gut tridecapeptide that functions as a neurotransmitter/neuromodulator in the central nervous system (CNS) and as an endocrine agent in the periphery. NT has numerous physiologic effects on multiple organs. This review will focus on the effects
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