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Merck
모든 사진(2)

주요 문서

SAB4200023

Sigma-Aldrich

Anti-VPS4B antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-SKD1, Anti-SKD1-homolog, Anti-SKD1A, Anti-SKD2, Anti-VPS4, Anti-VPS4-1, Anti-Vacuolar protein sorting 4 homolog A, Anti-Vacuolar protein sorting factor 4A

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen ~50 kDa

종 반응성

human, mouse

농도

~1.0 mg/mL

기술

immunoprecipitation (IP): 10-20 μg using lysate of mouse 3T3 cells
western blot: 2-4 μg/mL using whole extracts of G361 cells

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... VPS4B(9525)

일반 설명

Vacuolar protein sorting 4 homolog B (Vps4B) is a member of the AAA protein family (ATPases associated with diverse cellular activities) and is a homolog of yeast Vps4 protein. In humans, two of yeast protein paralogs have been identified as Vps4A and Vps4B. Both share high degree of amino acid sequence. The gene for Vps4B resides on human chromosome 18.

애플리케이션

Anti-VPS4B antibody produced in rabbit has been used in immunoblotting and immunoprecipitation.

생화학적/생리학적 작용

Vacuolar protein sorting 4 (Vps4) mediates endosomal membrane protein sorting, retroviral budding, and cytokinesis by recognizing membrane-associated endosomal sorting complexes required for transport (ESCRT-III) assemblies and catalysing their disassembly.

물리적 형태

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Luana L Scheffer et al.
Nature communications, 5, 5646-5646 (2014-12-24)
In muscle and other mechanically active tissue, cell membranes are constantly injured, and their repair depends on the injury-induced increase in cytosolic calcium. Here, we show that injury-triggered Ca(2+) increase results in assembly of ESCRT III and accessory proteins at
Comparative sequence and expression analyses of four mammalian VPS4 genes
Beyer A, et al.
Gene, 305(1), 47-59 (2003)
Membrane scission by the ESCRT-III complex
Wollert T, et al.
Nature, 458(7235), 172-172 (2009)

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