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Merck
모든 사진(1)

주요 문서

SAB3701061

Sigma-Aldrich

Anti-Mouse IgG IgA IgM (H+L), F(ab′)2 fragment, highly cross adsorbed-Texas Red™ antibody produced in goat

affinity isolated antibody, lyophilized powder

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.46

생물학적 소스

goat

Quality Level

결합

Texas Red® conjugate

항체 형태

affinity isolated antibody

항체 생산 유형

secondary antibodies

클론

polyclonal

양식

lyophilized powder

종 반응성

mouse

기술

direct immunofluorescence: suitable
indirect ELISA: suitable
indirect immunofluorescence: suitable

배송 상태

wet ice

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

일반 설명

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity. IgA molecules in the serum are mostly dimeric. IgA is found in saliva, tracheobronchial secretions, genito urinary secretions, milk and colostrum. IgM is present on the surface of B lymphocytes in its monomeric form.

특이성

This product was prepared from polyspecific antiserum by immunoaffinity chromatography using antigens coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Goat Serum. No reaction was observed against Anti-Goat IgG F(c), Anti-Pepsin or Human Serum Proteins. This product is suitable for the detection of all Human immunoglobulin classes, isotypes and chain combinations.

면역원

Mouse IgG IgA and IgM whole molecule

생화학적/생리학적 작용

Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. IgG2a of IgG has cytotropic properties and IgG2 molecules has the ability to activate complement.

물리적 특성

Antibody format: IgG F(ab′)2

물리적 형태

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

재구성

Reconstitute with 1.0 mL deionized water (or equivalent).

법적 정보

Texas Red is a registered trademark of Life Technologies

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픽토그램

Skull and crossbonesEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2

보충제 위험성

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Molecular Genetics of Immunoglobulin (1987)
The Immunoglobulins: Structure and Function (1998)
The Laboratory Rat (2005)
Specific IgG for cat allergens in patients with allergic conjunctivitis.
Miyama A, et al.
International Ophthalmology, 35(4), 575-586 (2015)
Antibody structure, instability, and formulation.
Wang W
Journal of Pharmaceutical Sciences, 96(1), 1-26 (2007)

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