SAB3500070

Anti-THEM2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): Anti-ACOT13, Anti-Acyl-CoA thioesterase 13, Anti-PNAS-27, Anti-Thioesterase superfamily member 2
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 종 반응성: rat, mouse, human
• 기술: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• NCBI 수납 번호: NP_060943
• UniProt 수납 번호: Q9NPJ3
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ACOT13(55856)

설명

일반 설명

Acyl-CoA thioesterase 13 (ACOT13), also known as thioesterase superfamily member 2 (THEM-2), is encoded by the gene mapped to human chromosome 6p22.3. The encoded protein has a molecular mass of ∼15kDa with 140 amino acids. It is a member of the hotdog-domain thioesterase family. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brown adipose tissue (BAT). It has been shown to be co-localized with β-tubulin on microtubules. At least two isoforms of THEM2 are known to exist.

면역원

THEM2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THEM2.

생화학적/생리학적 작용

Acyl-CoA thioesterase 13 (ACOT13)/thioesterase superfamily member 2 (THEM-2) possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 associates with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids.

특징 및 장점

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결합

The action of this antibody can be blocked using blocking peptide SBP3500070.

물리적 형태

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable