S5013

Salbutamol hemisulfate salt

≥98%

• 동의어(들): α-([t-Butylamino]methyl)-4-hydroxy-m-xylene-α,α′-diol, Albuterol
• Linear Formula: C₁₃H₂₁NO₃ · 1/2H₂SO₄
• CAS Number: 51022-70-9
• Molecular Weight: 288.35
• EC Number: 256-916-8
• MDL number: MFCD00055200
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277746
• NACRES: NA.77

속성

• Quality Level: 200
• 분석: ≥98%
• solubility: 1 M NaOH: 50 mg/ml, clear to slightly hazy, yellow-green
• 주관자: GlaxoSmithKline
• SMILES string: OS(O)(=O)=O.CC(C)(C)NCC(O)c1ccc(O)c(CO)c1.CC(C)(C)NCC(O)c2ccc(O)c(CO)c2
• InChI: 1S/2C13H21NO3.H2O4S/c2*1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h2*4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4)
• InChI key: BNPSSFBOAGDEEL-UHFFFAOYSA-N
• 유전자 정보: human ... ADRB2(154)

설명

애플리케이션

Salbutamol hemisulfate salt has been used as reference standards of drugs for the validation of β-agonist residue.

Salbutamol hemisulfate salt was used as standard in analysis of fortified meat for LABA content using ELISA kits.³ It was used to study the response of prostaglandin 2α to various β-adrenergic agonists in cultured bovine endometrial cells.⁴

생화학적/생리학적 작용

β2-Adrenergic receptor agonist.

Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP). Salbutamol is particularly effective in treatment of asthma as it provides immediate relief. Salbutamol is one of the most popular short-acting BA (SABA). It is useful in treating the symptoms of EIB (exercise induced bronchospasm).

Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP).¹ Salbutamol is particularly effective in treatment of asthma as it provides immediate relief.²

특징 및 장점

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H317,H351,H361fd
• 예방조치 성명서: P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
• Hazard Classifications: Carc. 2 - Repr. 2 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)