S1141
Spermine tetrahydrochloride
BioReagent
동의어(들):
N,N′-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C10H26N4 · 4HCl
CAS Number:
Molecular Weight:
348.18
Beilstein:
3911771
EC Number:
MDL number:
UNSPSC 코드:
12352116
PubChem Substance ID:
NACRES:
NA.52
추천 제품
Grade
Molecular Biology
Quality Level
제품 라인
BioReagent
양식
solid
mp
310-311 °C (dec.) (lit.)
solubility
H2O: soluble 100 mg/mL, clear, colorless to light yellow
외래 활성
DNase, RNase, protease, NICKase, none detected
저장 온도
room temp
SMILES string
Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN
InChI
1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
InChI key
XLDKUDAXZWHPFH-UHFFFAOYSA-N
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관련 카테고리
일반 설명
Spermine is a polyamine involved in cellular metabolism and DNA stabilization. In molecular biology it can be used in buffers for purification of DNA.
애플리케이션
Used to precipitate DNA from low salt aqueous buffers.
생화학적/생리학적 작용
Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Mixed NMDA agonist/antagonist at the polyamine site. Role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
D M Hougaard et al.
The Biochemical journal, 238(1), 43-47 (1986-08-15)
Two recently developed fluorescence cytochemical methods, specific for spermidine and spermine, were used to localize polyamines in the endocrine pancreas. The polyamines were restricted to the insulin-producing beta-cells and were mainly associated with the secretory granules. Chemical polyamine determinations carried
Binh V Vu et al.
PloS one, 7(12), e51863-e51863 (2013-01-04)
While most nucleic acids are intracellular, trace amounts of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), including micro RNAs, can also be found in peripheral blood. Many studies have suggested the potential utility of these circulating nucleic acids in prenatal
L L Vindeløv et al.
Cancer research, 40(11), 4295-4300 (1980-11-01)
Flow-cytometric DNA analysis yields information on ploidy and proliferative characteristics of a cell population. The analysis was implemented on small-cell anaplastic carcinoma of the lung using a rapid detergent technique for the preparation of fine-needle aspirates for DNA determination and
Aracely A Lutes et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(24), 9910-9915 (2011-05-06)
Speciation in animals commonly involves an extrinsic barrier to genetic exchange followed by the accumulation of sufficient genetic variation to impede subsequent productive interbreeding. All-female species of whiptail lizards, which originated by interspecific hybridization between sexual progenitors, are an exception
D C Allison et al.
Annals of surgery, 214(6), 648-656 (1991-12-01)
The DNA content of 47 adenocarcinomas arising in the head of the pancreas from patients who had undergone successful pancreatoduodenectomy was measured. The DNA measurements of each tumor were made without knowledge of the clinical course by absorption cytometry performed
프로토콜
This product is suitable for DNA precipitation from low salt aqueous buffers. It has been tested for the absence of proteases and nucleases.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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