추천 제품
종 반응성
human
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
입력
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2.5 pg/mL
standard curve range: 2.44-10000 pg/mL
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
human ... APOC3(345)
일반 설명
The antibody pair provided in this kit recognizes Human Apolipoprotein C3.
ApoC-III is a glycoprotein that has 79 amino acids. It is coded by APOC3 gene. APOC3 is expressed in the liver and intestine. This gene is located on human chromosome 11.
ApoC-III is a glycoprotein that has 79 amino acids. It is coded by APOC3 gene. APOC3 is expressed in the liver and intestine. This gene is located on human chromosome 11.
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
생화학적/생리학적 작용
Apolipoprotein C-III (APOC3) has the ability to prevent lipoprotein lipase (LPL) and hepatic lipase activity. It is considered as a major modulator of triglyceride metabolism.
기타 정보
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Targeting APOC3 in the familial chylomicronemia syndrome.
Gaudet D, et al.
The New England Journal of Medicine, 371(23), 2200-2206 (2014)
Apolipoprotein CIII Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study.
van Capelleveen JC, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 37(6), 1206-1212 (2017)
A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels.
Khetarpal SA, et al.
Nature Medicine, 23(9), 1086-1086 (2017)
Role of ApoCs in lipoprotein metabolism: functional differences between ApoC1, ApoC2, and ApoC3.
Jong MC, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 19(3), 472-484 (1999)
Keishi Hata et al.
Biomedical research (Tokyo, Japan), 41(1), 33-42 (2020-02-25)
We investigated lipid metabolism in PXB-cells, which are human primary hepatocytes isolated from liver-humanized mice, and HepG2 and HuH-7 human hepatoma cell lines. Lipoprotein levels were higher in PXB-cells than in the 2 other cell lines, and PXB-cells mainly released
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