PZ0323

PF-06767832

≥98% (HPLC)

• 동의어(들): 1,5-Anhydro-2,3-dideoxy-3-[[[5-methyl-4-[[4-(4-thiazolyl)phenyl]methyl]-2-pyridinyl]carbonyl]amino]-L-threo-pentitol, N-((3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl)-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide, PF 6767832
• 실험식(Hill 표기법): C₂₂H₂₃N₃O₃S
• CAS Number: 1859081-58-5
• Molecular Weight: 409.50
• UNSPSC 코드: 51111800
• PubChem Substance ID: 329823840
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 30 mg/mL, clear
• 저장 온도: room temp
• SMILES string: CC1=CN=C(C(N[C@@H]2[C@@H](O)COCC2)=O)C=C1CC3=CC=C(C4=CSC=N4)C=C3
• InChI: 1S/C22H23N3O3S/c1-14-10-23-19(22(27)25-18-6-7-28-11-21(18)26)9-17(14)8-15-2-4-16(5-3-15)20-12-29-13-24-20/h2-5,9-10,12-13,18,21,26H,6-8,11H2,1H3,(H,25,27)/t18-,21-/m0/s1
• InChI key: VVZZHFMLRHJXTO-RXVVDRJESA-N

설명

생화학적/생리학적 작용

PF-06767832 is a cell permeable, potent and selective M1 muscarinic acetylcholine receptor Positive Allosteric Modulator (PAM). Studies have shown that PF-06767832 potentiates the activity of acetylcholine (Ach) in vitro.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable