PZ0259

PH-797804

≥98% (HPLC)

• 동의어(들): 3-Bromo-4-[(2,4-difluorobenzyl)oxy]-1-[5-[(methylamino)carbonyl]-2-methylphenyl]-6-methylpyridin-2(1H)-one, 3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethyl-benzamide, PH 797804
• 실험식(Hill 표기법): C₂₂H₁₉BrF₂N₂O₃
• CAS Number: 586379-66-0
• Molecular Weight: 477.30
• MDL number: MFCD18251426
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329823795
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 10 mg/mL, clear
• 저장 온도: 20-25°C
• SMILES string: CC1=CC(OCC2=C(F)C=C(F)C=C2)=C(Br)C(N1C3=CC(C(NC)=O)=CC=C3C)=O
• InChI: 1S/C22H19BrF2N2O3/c1-12-4-5-14(21(28)26-3)9-18(12)27-13(2)8-19(20(23)22(27)29)30-11-15-6-7-16(24)10-17(15)25/h4-10H,11H2,1-3H3,(H,26,28)
• InChI key: KCAJXIDMCNPGHZ-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

PH-797804 is an orally active, potent and readily reversible ATP competitive inhibitor of the alpha isoform of human p38 MAP kinase. PH-797804 blocks inflammation-induced production of cytokines and proinflammatory mediators.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable