PZ0175

PD 149163 tetrahydrochloride hydrate

≥90% (HPLC)

• 동의어(들): N2-[(2S)-2,6-Diaminohexyl]-L-lysyl-L-prolyl-L-tryptophyl-3-methyl-L-valyl-L-Leucine ethyl ester tetrahydrochloride hydrate
• 실험식(Hill 표기법): C₄₂H₇₁N₉O₆·4HCl · xH₂O
• Molecular Weight: 943.91 (anhydrous basis)
• MDL number: MFCD20527308
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329823749
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥90% (HPLC)
• 양식: powder (Hygroscopic)
• 저장 조건: desiccated
• 색상: white to tan
• solubility: H₂O: ≥12 mg/mL
• 저장 온도: 2-8°C
• SMILES string: O.Cl.Cl.Cl.Cl.CCOC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCCN)NC[C@@H](N)CCCCN)C(C)(C)C
• InChI: 1S/C42H71N9O6.4ClH.H2O/c1-7-57-41(56)34(23-27(2)3)49-39(54)36(42(4,5)6)50-37(52)33(24-28-25-46-31-17-9-8-16-30(28)31)48-38(53)35-19-14-22-51(35)40(55)32(18-11-13-21-44)47-26-29(45)15-10-12-20-43;;;;;/h8-9,16-17,25,27,29,32-36,46-47H,7,10-15,18-24,26,43-45H2,1-6H3,(H,48,53)(H,49,54)(H,50,52);4*1H;1H2/t29-,32-,33-,34-,35-,36+;;;;;/m0...../s1
• InChI key: PIFVEGOSSWCHFK-AEPODNBTSA-N

설명

생화학적/생리학적 작용

PD 149163 is a Neurotensin NTR1 receptor agonist; a Neurotensin (8-13) analog. PD149163 is a selective, brain penetrating NT1 receptor agonist with pro-cognitive, antipsychotic and anxiolytic effects.

PD 149163 is a neurotensin (8-13) analog; Neurotensin NTR1 receptor agonist

특징 및 장점

This compound is featured on the Neurotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H319,H335
• 예방조치 성명서: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable