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Merck
모든 사진(2)

주요 문서

PRS4101

Sigma-Aldrich

Anti-Neuritin antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-Cpg15, Anti-NRN1, Anti-Neuritin 1

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.43

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

predicted mol wt 16 kDa

종 반응성

mouse, human

기술

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... NRN1(51299)

일반 설명

Neuritin (NRN1) is a candidate plasticity associated gene, that is a member of the neurotrophic factor family. It is also known as CPG15. It is expressed in the liver, heart, lungs, skeletal muscle and other normal organs along with the nervous system. It is also expressed in gastric cancer tissues. It is mapped to chromosome 6p24-p2.

면역원

a 20 amino acid peptide from near the center of human neuritin.

애플리케이션

Anti-Neuritin has been used in immunohistochemistry and western blotting.

생화학적/생리학적 작용

In gastric cancer treatment, neuritin (NRN1) serves as a potential target. It also participates in the pathogenesis of tumors. It plays a major role in the nervous system and on the migration, senescence, proliferation, and viability of stem cells.

결합

The action of this antibody can be blocked using blocking peptide SBP4101.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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관련 제품

제품 번호
설명
가격

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Shuhei Kamada et al.
Frontiers in oncology, 11, 758503-758503 (2021-11-23)
Acquired therapeutic resistance and metastasis/recurrence remain significant challenge in advance renal cell carcinoma (RCC), thus the establishment of patient-derived cancer models may provide a clue to assess the problem. We recently characterized that neuritogenesis-related protein neuritin 1 (NRN1) functions as
Effects of neuritin on the migration, senescence and proliferation of human bone marrow mesenchymal stem cells
Wang X, et al.
Cellular & Molecular Biology Letters, 20(3), 466-474 (2015)
Overexpression of neuritin in gastric cancer
Yuan M, et al.
Oncology Letters, 10(6), 3832-3836 (2015)
Impact of Neuritin 1 (NRN1) polymorphisms on fluid intelligence in schizophrenia
Chandler D, et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 153B(2), 428-437 (2010)
Ming Yuan et al.
Oncology letters, 10(6), 3832-3836 (2016-01-21)
The aim of the present study was to investigate the expression of neuritin in gastric cancer tissues, in order to explore the association between the expression of neuritin and the occurrence and development of gastric cancer. Tissue specimens were collected

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