P9864

PTP-β human

≥90%, recombinant, expressed in E. coli K12, GST-tagged, buffered aqueous glycerol solution, ≥50,000 units/mg protein

• 동의어(들): Protein Tyrosine Phosphatase-β
• CAS Number: 300853-81-0
• MDL number: MFCD02688688
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 생물학적 소스: human
• Quality Level: 200
• 재조합: expressed in E. coli K12
• 분석: ≥90%
• 양식: buffered aqueous glycerol solution
• 특이 활성도: ≥50,000 units/mg protein
• 분자량: ~250 kDa
• UniProt 수납 번호: P23467
• 응용 분야: cell analysis
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... PTPRB(5787)

설명

일반 설명

Protein tyrosine phosphatase, receptor type B (PTPRB), also known as vascular endothelial-protein-tyrosine phosphatase (VE-PTP), might have a role in remodeling of blood vessels and in angiogenesis. The gene encoding it is localized on human chromosome 12q15. It is also important for endothelial cell migration. The protein also controls the phosphorylation state of the angiopoietin receptor, Tie-2. PTPRB may modulate sodium channels by influencing the tyrosine phosphorylation status.

생화학적/생리학적 작용

Dephosphorylates tyrosine proteins.

단위 정의

One unit of PTP-β will hydrolyze 1.0 nanomole of p-nitrophenyl phosphate per min at 30 °C.

물리적 형태

solution in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCL, 3 mM DTT, 16 mM glutathione and 20% glycerol

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable