Name: Prostaglandin E<SUB>1</SUB>
Brand: SIGMA

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About This Item

실험식(Hill 표기법):

C₂₀H₃₄O₅

CAS Number:

745-65-3

Molecular Weight:

354.48

Beilstein:

5294062

EC Number:

212-017-2

MDL number:

MFCD00077860

UNSPSC 코드:

12352209

PubChem Substance ID:

24898855

NACRES:

NA.77

기술 서비스

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도움 문의

생물학적 소스

synthetic (organic)

Quality Level

200

무균

γ-irradiated

제품 라인

BioXtra

분석

≥60% (HPLC)

양식

powder

농도

≥60% (HPLC)

기술

cell culture | mammalian: suitable

solubility

ethanol: 1 mg/mL

저장 온도

−20°C

SMILES string

O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1

InChI

1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

InChI key

GMVPRGQOIOIIMI-DWKJAMRDSA-N

유전자 정보

human ... PTGER1(5731), PTGER2(5732), PTGIR(5739)
mouse ... Ptger1(19216), Ptger2(19217), Ptger3(19218), Ptger4(19219)

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애플리케이션

For use in cell culture applications for the study of prostaglandin regulated cell signaling and gene regulation.

Prostaglandin E1 has been used in maintaining mice proximal tubule, and NRK-52E, a rat renal epithelial cell line.

생화학적/생리학적 작용

Prostaglandins mediate vasodilation and vasoconstriction, the E series of prostaglandin is a highly effective vasodilator. It is known to efficiently cause erythema. Prostaglandin E1 is considered as a potent pyretic factor, and acts through cerebral ventricles. Prostaglandin E1 is useful to prolong cardiovascular function in new born suffering from ductus-dependant congenital heart disease until surgery.