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Merck
모든 사진(1)

주요 문서

P5556

Sigma-Aldrich

Poloxamer 188 solution

10%, sterile-filtered, BioReagent, suitable for insect cell culture

동의어(들):

Nonionic copolymer surfactant

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12161902
PubChem Substance ID:
NACRES:
NA.75

설명

non-ionic

무균

sterile-filtered

제품 라인

BioReagent

분자량

average mol wt 8350

농도

10%

기술

cell culture | insect: suitable

불순물

endotoxin, tested

전이 온도

cloud point ≥100

HLB

29

SMILES string

O2C(C2)C.O1CC1

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

일반 설명

Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer. It comprises a central chain of hydrophobic polyoxypropylene flanked at ends by hydrophilic polyoxyethylene.

애플리케이션

A nonionic copolymer surfactant

생화학적/생리학적 작용

Poloxamer 188 (P188) elicits hemorheological, antithrombotic, anti-inflammatory, and cytoprotective activities. It restores and stabilizes membrane barrier function. P188 also inhibits lipid peroxidation, reduces surface tension and hydrophobic-based cellular adherence. P-188 exhibits low toxicity and may be used in oral drug delivery.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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