P0869

Monoclonal Anti-Peroxisome Proliferator Activated Receptor α antibody produced in mouse

~1 mg/mL, clone 3B6/PPAR, purified immunoglobulin, buffered aqueous solution

• 동의어(들): Anti-PPARα
• MDL number: MFCD01092469
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 3B6/PPAR, monoclonal
• 양식: buffered aqueous solution
• 종 반응성: mouse, rat, human
• 농도: ~1 mg/mL
• 기술: western blot: 2-5 μg/mL using human, mouse and rat
• 동형: IgG2b
• UniProt 수납 번호: Q07869
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PPARA(5465) ; mouse ... Ppara(19013) ; rat ... Ppara(25747)

설명

일반 설명

Peroxisome proliferator-activated receptors (PPARs) are a group of closely related nuclear receptors. Three PPAR isotypes have been identified: α,β (also called NUC1) and γ. PPARa mRNA is expressed most in brown adipose tissue, heart, liver and kidney in rats. The gene encoding PPARα is localized on human chromosome 22q12-q13.1 and rat chromosome 7q34.

면역원

purified recombinant PPARα protein.

생화학적/생리학적 작용

Peroxisome proliferator-activated receptors (PPARs) may be involved in chronic diseases such as diabetes, obesity, atherosclerosis and cancer. PPARα has a protective function in fatty acids overload associated tubular injury. The enzyme also has a role in fatty acid oxidation and metabolism.

물리적 형태

Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin and 0.05% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable