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Merck
모든 사진(3)

주요 문서

N6136

Sigma-Aldrich

Nickel(II) chloride hexahydrate

BioReagent, suitable for cell culture

동의어(들):

NiCl2.6H2O, Nickel chloride hexahydrate, Nickel dichloride hexahydrate

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About This Item

Linear Formula:
NiCl2 · 6H2O
CAS Number:
Molecular Weight:
237.69
MDL number:
UNSPSC 코드:
12352207
PubChem Substance ID:
NACRES:
NA.71

제품 라인

BioReagent

Quality Level

양식

powder

기술

cell culture | mammalian: suitable

SMILES string

[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].Cl[Ni]Cl

InChI

1S/2ClH.Ni.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2

InChI key

LAIZPRYFQUWUBN-UHFFFAOYSA-L

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애플리케이션

Nickel(II) chloride hexahydrate has been used:
  • in the preparation of nickel platting solution for galvanostatically coating nickel inside the reduced carbon layer during the synthesis of multiwall carbon nanotube micromotors
  • in screening of metals for inflammatory effect on vascular endothelial cells
  • as an additive in artificial cerebrospinal fluid (ACSF) to analyse excitatory post synaptic currents (EPSPs) in the hippocampus slices

생화학적/생리학적 작용

Nickel (Ni) is an essential trace element that plays an important role in the structure and function of DNA, RNA and protein. It has toxic effects on renal, pulmonary and cardiovascular system at higher concentrations. Nickel is implicated in carcinogenesis. Ni2+ ions is a clastogenic agent. Nickel ions (Ni2+) is a non-specific voltage-gated calcium channel blocker.

픽토그램

Skull and crossbonesHealth hazardEnvironment

신호어

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A Inhalation - Muta. 2 - Repr. 1B - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Inhalation

표적 기관

Lungs

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Effects of chemostimuli on [Ca2+] i responses of rat aortic body type I cells and endogenous local neurons: comparison with carotid body cells
Piskuric NA and Nurse CA
The Journal of Physiology, 590(9), 2121-2135 (2012)
Surfactant-Free beta-Galactosidase Micromotors for ?On-The-Move? Lactose Hydrolysis
Maria-Hormigos R, et al.
Advances in Functional Materials, 28(25), 1704256-1704256 (2018)
Functional coupling of Cav2.3 and BK potassium channels regulates action potential repolarization and short-term plasticity in the mouse hippocampus
Gutzmann JJ, et al.
Frontiers in Cellular Neuroscience, 13(3), 492-499 (2019)
Studies on the genotoxic effect of nickel chloride in mice and the possible protective role of soybean seeds extracts
Fahmy MA, et al.
Global Journal of Pharmacology, 8(4), 625-634 (2014)
Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium
Salnikow K and Zhitkovich A
Chemical Research in Toxicology, 21(1), 28-44 (2007)

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