N4382

Nalidixic acid sodium salt

powder

• 동의어(들): 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt
• 실험식(Hill 표기법): C₁₂H₁₁N₂NaO₃
• CAS Number: 3374-05-8
• Molecular Weight: 254.22
• Beilstein: 3580062
• EC Number: 222-159-7
• MDL number: MFCD00064376
• UNSPSC 코드: 12352106
• PubChem Substance ID: 24278589
• NACRES: NA.77

속성

• 양식: powder
• Quality Level: 200
• 항생제 활성 스펙트럼: Gram-negative bacteria; Gram-positive bacteria
• 동작 모드: DNA synthesis | interferes; enzyme | inhibits
• 주관자: Sanofi Aventis
• SMILES string: [Na+].CCN1C=C(C([O-])=O)C(=O)c2ccc(C)nc12
• InChI: 1S/C12H12N2O3.Na/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;/h4-6H,3H2,1-2H3,(H,16,17);/q;+1/p-1
• InChI key: ROKRAUFZFDQWLE-UHFFFAOYSA-M

설명

일반 설명

Chemical structure: quinolone

Nalidixic acid is a quinolone and can block the activity of bacterial topoisomerase type II enzyme, thereby stopping bacterial replication. It is a potential antibacterial agent against Gram-negative bacteria than Gram-positive bacteria. Nalidixic acid has been studied in the management of urinary tract infections.

애플리케이션

Nalidixicacid has been used to treat the bacterial cultures to study itsresistance on Salmonella enterica and SalmonellaTyphimurium.

생화학적/생리학적 작용

Nalidixic acid sodium salt is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae.

특징 및 장점

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H351
• 예방조치 성명서: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves