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Merck
모든 사진(3)

주요 문서

M1255

Sigma-Aldrich

Calcein Blue

Powder

동의어(들):

4-Methylumbelliferone-8-methyliminodiacetic acid

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About This Item

실험식(Hill 표기법):
C15H15NO7
CAS Number:
Molecular Weight:
321.28
EC Number:
MDL number:
UNSPSC 코드:
12171500
PubChem Substance ID:
NACRES:
NA.47

제품명

Calcein Blue, fluorescent dye

Quality Level

양식

powder

기술

titration: suitable

색상

white to light yellow

solubility

1 M NaOH: 50 mg/mL

형광

λex 322 nm; λem 445 nm in methanol

적합성

suitable for indicator for EDTA titration

응용 분야

diagnostic assay manufacturing
hematology
histology

저장 온도

room temp

SMILES string

CC1=CC(=O)Oc2c(CN(CC(O)=O)CC(O)=O)c(O)ccc12

InChI

1S/C15H15NO7/c1-8-4-14(22)23-15-9(8)2-3-11(17)10(15)5-16(6-12(18)19)7-13(20)21/h2-4,17H,5-7H2,1H3,(H,18,19)(H,20,21)

InChI key

RJPSHDMGSVVHFA-UHFFFAOYSA-N

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일반 설명

Calcein Blue is a cell-permeable dye that stains viable cells. Upon entering the cell, intracellular esterases cleave the acetoxymethyl (AM) ester group, yielding the membrane-impermeable Calcein Blue fluorescent dye. The staining applications of Calcein blue include tumor tissues, mineralized tissues, bone, amino acids, and many more.

애플리케이션

Calcein blue has been used fluorescent labeling of the mineralised sections of bone. Calcein blue AM ester hydrolyzed to calcein blue is suitable as a a viability stain, both microscopically, and in fluorescence activated cell sorting systems. It is also used as a merker of living cells like Schwann cells at neuromuscular junctions.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

Indicators: International Series of Monographs in Analytical Chemistry (2013)
Juhyun Oh et al.
Aging, 8(11), 2871-2896 (2016-11-18)
Skeletal muscle is a highly regenerative tissue, but muscle repair potential is increasingly compromised with advancing age. In this study, we demonstrate that increased NF-κB activity in aged muscle fibers contributes to diminished myogenic potential of their associated satellite cells.
Zachary J Reitman et al.
Nature communications, 10(1), 3731-3731 (2019-08-21)
Pilocytic astrocytoma (PA), the most common childhood brain tumor, is a low-grade glioma with a single driver BRAF rearrangement. Here, we perform scRNAseq in six PAs using methods that enabled detection of the rearrangement. When compared to higher-grade gliomas, a
Tobias A Fuchs et al.
The Journal of cell biology, 176(2), 231-241 (2007-01-11)
Neutrophil extracellular traps (NETs) are extracellular structures composed of chromatin and granule proteins that bind and kill microorganisms. We show that upon stimulation, the nuclei of neutrophils lose their shape, and the eu- and heterochromatin homogenize. Later, the nuclear envelope
T Lymphocytes Influence the Mineralization Process of Bone.
El Khassawna T
Frontiers in Immunology, 8, 562-562 (2017)

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