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Merck
모든 사진(1)

주요 문서

M110

Sigma-Aldrich

α-Methylserotonin maleate salt

≥98% (HPLC)

동의어(들):

α-Methyl-5-hydroxytryptamine maleate salt, (±)-3-(2-Aminopropyl)indol-5-ol maleate salt

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About This Item

실험식(Hill 표기법):
C11H14N2O · C4H4O4
CAS Number:
Molecular Weight:
306.31
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥98% (HPLC)

양식

powder

색상

white to beige

solubility

H2O: >3 mg/mL, clear (warmed)

저장 온도

−20°C

SMILES string

[H]\C(=C(/[H])C(O)=O)C(O)=O.CC(N)Cc1c[nH]c2ccc(O)cc12

InChI

1S/C11H14N2O.C4H4O4/c1-7(12)4-8-6-13-11-3-2-9(14)5-10(8)11;5-3(6)1-2-4(7)8/h2-3,5-7,13-14H,4,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

YQNHFSXRABPJLP-BTJKTKAUSA-N

유전자 정보

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

5-HT2 serotonin receptor agonist.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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Ralf Buettner et al.
Molecular therapy oncolytics, 14, 149-158 (2019-06-19)
The immunosuppressive agent leflunomide has been used in the treatment of over 300,000 patients with rheumatoid arthritis. Its active metabolite, teriflunomide (Ter), directly inhibits dihydroorotate dehydrogenase (DHODH), an enzyme involved in nucleoside synthesis. We report that Ter not only shows
P D Feldman
Journal of the autonomic nervous system, 56(1-2), 119-124 (1995-12-05)
Spontaneous neuronal activity in the solitary tract nucleus was recorded extracellularly in a brain slice preparation during bath-application of 5-HT1 and 5-HT2 receptor-selective agonists and antagonists. The 5-HT1A/5-HT1B agonist 5-carboxamidotryptamine depressed activity in 20 of 25 neurons studied. The remaining
A M Ismaiel et al.
Journal of medicinal chemistry, 33(2), 755-758 (1990-02-01)
alpha-Methyl-5-hydroxytryptamine (alpha-Me-5-HT; 2) and 2-methyl-5-hydroxytryptamine (2-Me-5-HT; 3) are considered to be 5-HT2-selective and 5-HT3-selective agents, respectively. These agents were synthesized and examined at serotonin (5-HT) binding sites because there is relatively little documentation as to their selectivity and because they
G P Leung et al.
The Journal of physiology, 519 Pt 3, 657-667 (1999-08-24)
1. The short-circuit current (Isc) technique was used to study the role of 5-hydroxytryptamine (5-HT) in the regulation of anion secretion in cultured rat cauda epididymal epithelia. 2. 5-HT, the 5-HT1B-selective agonist 5-nonyloxytryptamine (5-NOT) and the 5-HT2B-selective agonist alpha-methyl-5-hydroxytryptamine (alpha-methyl-5-HT)

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