M006
Proglumide sodium salt
solid
동의어(들):
4-Benzoylamino-5-dipropylamino-5-oxopentanoic acid sodium-potassium salt, N-Benzoyl-N′,N′-dipropyl-DL-isoglutamine sodium-potassium salt
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모든 사진(3)
About This Item
실험식(Hill 표기법):
C18H25N2NaO4
CAS Number:
Molecular Weight:
356.39
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
양식
solid
Quality Level
색상
white
solubility
H2O: soluble
SMILES string
[Na+].CCCN(CCC)C(=O)C(CCC([O-])=O)NC(=O)c1ccccc1
InChI
1S/C18H26N2O4.Na/c1-3-12-20(13-4-2)18(24)15(10-11-16(21)22)19-17(23)14-8-6-5-7-9-14;/h5-9,15H,3-4,10-13H2,1-2H3,(H,19,23)(H,21,22);/q;+1/p-1
InChI key
UFMWGCINVOIJSO-UHFFFAOYSA-M
유전자 정보
human ... CCK(885) , CCKAR(886) , CCKBR(887)
mouse ... CCK(12424)
rat ... CCK(25298)
애플리케이션
Proglumide sodium salt has been used to study the effects of proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L.
생화학적/생리학적 작용
CCK antagonist; selectively blocks CNS effects.
Proglumide sodium salt is a non-peptide cholecystokinin receptor antagonist that has greater selectivity for the CCKA subtype. It selectively blocks central nervous system effects. Proglumide sodium salt is orally active.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
The cholecystokinin antagonist, proglumide, increases food intake in the rat
G.Shillabeer and J. Davidson
Regulatory Peptides (1984)
J V Menani et al.
The American journal of physiology, 275(5 Pt 2), R1431-R1437 (1998-10-29)
The present study investigated the effects of bilateral injections of the nonselective CCK receptor antagonist proglumide or CCK-8 into the lateral parabrachial nuclei (LPBN) on the ingestion of 0.3 M NaCl and water induced by intracerebroventricular injection of ANG II
E S Corp et al.
Physiology & behavior, 61(6), 823-827 (1997-06-01)
Cholecystokinin (CCK) receptors are classified as two subtypes, designated CCK(A) and CCK(B), and both subtypes are found in brain and peripheral tissues of rats. CCK-8 has been shown to act peripherally to reduce meal size, and this satiating action can
Role of cholecystokinin and its antagonist proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L.
V. C. Rubio
Physiology & Behavior (2008)
James M Hill et al.
Science translational medicine, 6(265), 265ra169-265ra169 (2014-12-05)
Herpesviruses are highly prevalent and maintain lifelong latent reservoirs, thus posing challenges to the control of herpetic disease despite the availability of antiviral pharmaceuticals that target viral DNA replication. The initiation of herpes simplex virus infection and reactivation from latency
Chromatograms
application for HPLCapplication for HPLC자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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