추천 제품
생물학적 소스
egg yolk
Quality Level
설명
zwitterionic
유형
Type I
분석
≥99%
양식
powder
색상
white
작용기
phospholipid
지질 유형
phosphoglycerides
배송 상태
ambient
저장 온도
−20°C
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애플리케이션
L-α-Lysophosphatidylcholine from egg yolk has been used:
- as a surfactant
- as a media supplement and in Staphylococcus aureus inhibition assay in dermatitis
- as a demyelinating agent for nerve
- as a component in sperm nuclei preparation buffer
생화학적/생리학적 작용
Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun.
Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.
품질
Contains primarily palmitic and stearic acids.
제조 메모
Prepared by the action of phospholipase A on egg L-α-phosphatidylcholine.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
Christopher E McMurran et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(50), 25311-25321 (2019-11-20)
The microbiota is now recognized as a key influence on the host immune response in the central nervous system (CNS). As such, there has been some progress toward therapies that modulate the microbiota with the aim of limiting immune-mediated demyelination
Lauri J Lehto et al.
Frontiers in neuroscience, 11, 433-433 (2017-08-22)
In this work a new MRI modality entitled Relaxation Along a Fictitious Field in the rotating frame of rank 4 (RAFF4) was evaluated in its ability to detect lower myelin content in lysophosphatidyl choline (LPC)-induced demyelinating lesions. The lesions were
Isolation and demembranation of Xenopus sperm nuclei
Hazel JW and Gatlin JC
Cold Spring Harbor Protocols (2018)
RP-CARS: label-free optical readout of the myelin intrinsic healthiness
de Vito G, et al.
Optics Express, 22(11), 13733-13743 (2014)
Transplantation of human skin microbiota in models of atopic dermatitis
Myles IA, et al.
JCI insight, 1(10), 031712-031712 (2016)
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