I2273

3-Indoleacrylic acid

BioReagent, ≥98% (HPLC)

• 동의어(들): 3-(3-Indolyl)acrylic acid, IAA
• 실험식(Hill 표기법): C₁₁H₉NO₂
• CAS Number: 1204-06-4
• Molecular Weight: 187.19
• Beilstein: 6317
• EC Number: 214-872-7
• MDL number: MFCD00005633
• UNSPSC 코드: 12352106
• PubChem Substance ID: 24895972
• NACRES: NA.52

속성

• Grade: Molecular Biology
• Quality Level: 100
• 제품 라인: BioReagent
• 분석: ≥98% (HPLC)
• 양식: powder
• 분자량: 187.19 g/mol
• 저장 온도: room temp
• SMILES string: OC(=O)\C=C\c1c[nH]c2ccccc12
• InChI: 1S/C11H9NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-7,12H,(H,13,14)/b6-5+
• InChI key: PLVPPLCLBIEYEA-AATRIKPKSA-N

설명

일반 설명

3-Indoleacrylic acid (IAA) is a chemical used for the induction of gene transcription. This expression system requires that the gene of interest is cloned in plasmids containing the trpE promoter.

애플리케이션

3-Indoleacrylic acid has been used in the induction of ribokinase expression in E. coli.

생화학적/생리학적 작용

3-Indoleacrylic acid (IAA) is metabolized from tryptophan and this conversion is carried out by gut microflora. 3-Indoleacrylic acid (IAA) is a chemical used for the induction of gene transcription. The IAA induced expression system requires the gene of interest cloned in plasmids containing the trp promoter. It promotes the barrier functionality of the intestinal epithelial cells. IAA also favors anti-inflammatory response and is regarded as a potential therapeutic to treat inflammatory bowel disease (IBD). It is also implicated in a variety of cellular processes including apoptosis, autophagy, cell proliferation and migration. In tumor cells, IAA is also reported to hinder tryptophan metabolism.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves