I134

L-N⁵-(1-Iminoethyl)ornithine hydrochloride

≥95% (HPLC)

• 동의어(들): L-NIO hydrochloride, L-Ornithine ψ-acetamidine hydrochloride
• 실험식(Hill 표기법): C₇H₁₅N₃O₂ · xHCl
• CAS Number: 852173-80-9
• Molecular Weight: 173.21 (free base basis)
• MDL number: MFCD00153817
• UNSPSC 코드: 12352204
• PubChem Substance ID: 329815348
• NACRES: NA.26

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: powder
• 분자량: calculated mol wt 173.22 g/mol
• 저장 조건: desiccated; under inert gas
• 색상: white to beige
• solubility: H₂O: 2 mg/mL, clear (warmed)
• 저장 온도: −20°C
• SMILES string: CC(NCCC[C@H](N)C(O)=O)=N.[H]Cl
• InChI: 1S/C7H15N3O2.ClH/c1-5(8)10-4-2-3-6(9)7(11)12;/h6H,2-4,9H2,1H3,(H2,8,10)(H,11,12);1H/t6-;/m0./s1
• InChI key: JIBZSGQTCBWUKL-RGMNGODLSA-N

설명

애플리케이션

L-N⁵-(1-Iminoethyl) ornithine hydrochloride has been used to study the effects of the cytotoxic drug paclitaxel and carbachol (a cholinergic agonist) to induce death in breast tumor MCF-7 cells and the role of nitric oxide synthase (NOS) in this effect. It has also been used to study its effects on pulmonary arterial responses to sufentanil in the feline pulmonary vascular bed.

생화학적/생리학적 작용

A potent irreversible inhibitor of nitric oxide synthase.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves