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Merck
모든 사진(1)

주요 문서

H8664

Sigma-Aldrich

Steviol hydrate

≥98% (HPLC), powder

동의어(들):

(4α)-13-Hydroxykaur-16-en-18-oic acid hydrate

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About This Item

실험식(Hill 표기법):
C20H30O3 · xH2O
CAS Number:
Molecular Weight:
318.45 (anhydrous basis)
MDL number:
UNSPSC 코드:
12161501
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥98% (HPLC)

양식

powder

색상

white to tan

solubility

DMSO: >10 mg/mL

저장 온도

2-8°C

SMILES string

O.C[C@@]12CCC[C@](C)([C@H]1CC[C@]34CC(=C)[C@](O)(CC[C@@H]23)C4)C(O)=O

InChI

1S/C20H30O3.H2O/c1-13-11-19-9-5-14-17(2,7-4-8-18(14,3)16(21)22)15(19)6-10-20(13,23)12-19;/h14-15,23H,1,4-12H2,2-3H3,(H,21,22);1H2/t14-,15-,17+,18+,19+,20-;/m0./s1

InChI key

SGPAFVVDOPSBEU-CRRYNOPCSA-N

생화학적/생리학적 작용

Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters.
Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters. Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. Steviol is a useful tool for studying renal drug clearance.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

이미 열람한 고객

Slide 1 of 1

1 of 1

Stevioside primary reference standard

05420590

Stevioside

Venkata Sai Prakash Chaturvedula et al.
Molecules (Basel, Switzerland), 16(10), 8402-8409 (2011-10-05)
Synthesis of two ent-kaurane diterpene glycosides, steviol 19-O-β-D-glucopyranosiduronic acid (steviol glucuronide, 5), and 13-hydroxy ent-kaur-16-en-19-oic acid-β-D-glucopyranosyl ester (7) has been achieved from a common starting material, steviol, using phase transfer catalyst. Also, synthesis of an additional 17-nor-ent-kaurane glycoside, namely 13-methyl-16-oxo-17-nor-ent-kauran-19-oic
Ravil N Khaybullin et al.
Bioorganic & medicinal chemistry letters, 22(22), 6909-6913 (2012-10-11)
New derivatives of steviol 1, the aglycone of the glycosides of Stevia rebaudiana, including a novel class of semisynthetic diterpenoids, namely macrocyclic ent-kauranes were synthesized. These compounds possess antituberculosis activity inhibiting the in vitro growth of Mycobacterium Tuberculosis (H37R(V) strain)
Stijn Ceunen et al.
Plant science : an international journal of experimental plant biology, 198, 72-82 (2012-12-04)
The effect of photoperiodism on steviol glycoside (SVgly) accumulation was investigated in Stevia rebaudiana. Topped plants were cultivated to develop new branches under a 16h or 8h photoperiod. During different ontogenetic phases, leaves, stems, lateral shoots, roots and reproductive organs
Midori Takasaki et al.
Bioorganic & medicinal chemistry, 17(2), 600-605 (2009-01-10)
In a search for potential cancer chemopreventive agents from natural resources, stevioside (1), a sweetener, and six related compounds, including two aglycones steviol (6) and isosteviol (7), were screened in an in vitro assay for inhibitory effects on Epstein-Barr virus
[Steviol glycosides as sweetener in diabetes?].
K Tuttas et al.
Deutsche medizinische Wochenschrift (1946), 137(15), 806-806 (2012-04-12)

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