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Merck
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주요 문서

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G1260

Sigma-Aldrich

Gastrin II Sulfated

≥95% (HPLC), suitable for ligand binding assays

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About This Item

실험식(Hill 표기법):
C97H124N20O34S2
CAS Number:
19361-51-4
Molecular Weight:
2178.27
MDL number:
MFCD00133360
UNSPSC 코드:
12352209
PubChem Substance ID:
24895054
NACRES:
NA.26

제품명

Gastrin II Sulfated, ≥95% (HPLC)

Quality Level

200

분석

≥95% (HPLC)

양식

powder

기술

ligand binding assay: suitable

색상

white

UniProt 수납 번호

P01350

저장 온도

−20°C

SMILES string

CSCCC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(Cc3ccc(OS(O)(=O)=O)cc3)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(Cc4c[nH]c5ccccc45)NC(=O)C6CCCN6C(=O)CNC(=O)C7CCC(=O)N7)C(=O)NC(CC(O)=O)C(=O)NC(Cc8ccccc8)C(N)=O

InChI

1S/C97H124N20O34S2/c1-49(2)39-68(114-95(145)71(43-54-46-100-59-18-11-9-16-57(54)59)116-97(147)73-19-12-37-117(73)76(120)48-102-85(135)60-24-30-74(118)104-60)93(143)110-65(29-35-81(129)130)91(141)109-64(28-34-80(127)128)90(140)108-63(27-33-79(125)126)89(139)107-62(26-32-78(123)124)88(138)106-61(25-31-77(121)122)87(137)103-50(3)84(134)113-69(41-52-20-22-55(23-21-52)151-153(148,149)150)86(136)101-47-75(119)105-70(42-53-45-99-58-17-10-8-15-56(53)58)94(144)111-66(36-38-152-4)92(142)115-72(44-82(131)132)96(146)112-67(83(98)133)40-51-13-6-5-7-14-51/h5-11,13-18,20-23,45-46,49-50,60-73,99-100H,12,19,24-44,47-48H2,1-4H3,(H2,98,133)(H,101,136)(H,102,135)(H,103,137)(H,104,118)(H,105,119)(H,106,138)(H,107,139)(H,108,140)(H,109,141)(H,110,143)(H,111,144)(H,112,146)(H,113,134)(H,114,145)(H,115,142)(H,116,147)(H,121,122)(H,123,124)(H,125,126)(H,127,128)(H,129,130)(H,131,132)(H,148,149,150)

InChI key

WSLIFCVCCVWYQQ-UHFFFAOYSA-N

유전자 정보

human ... GAST(2520)

Amino Acid Sequence

pGlu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr(SO3H)-Gly-Trp-Met-Asp-Phe-NH2

생화학적/생리학적 작용

Gastrin II and Gastrin I are peptide hormones involved in gastrointestinal processes such as the stimulation of gastric (HCl) release.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
SLCM4159
SLCG2630
SLCF8850
SLBZ9762
SLBX2765

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문서 라이브러리 방문

T Sethi et al.
Cancer research, 52(21), 6031-6035 (1992-11-01)
Gastrin has been postulated to be a physiological growth factor, but compelling in vitro evidence of this has been difficult to obtain. In the present study we investigated whether small cell lung carcinoma cell lines could provide a useful model
I Gede Arinton
Acta medica Indonesiana, 42(3), 142-146 (2010-08-21)
to find out biomarker as diagnostic tool of H. pylori chronic gastritis. the design of present study was a diagnostic test and there were 104 subjects with H. pylori chronic gastritis who fulfilled the inclusion and exclusion criteria. The diagnosis
Saroj Kumari et al.
Chembiochem : a European journal of chemical biology, 13(2), 282-292 (2011-12-14)
Fluorescent labeling has enabled a better understanding of the relationships between receptor location, function, and life cycle. Each of these perspectives contributes new insights into drug action, particularly for G protein-coupled receptors (GPCRs). The aim of this study was to
A Botella et al.
Gastroenterology, 102(3), 779-786 (1992-03-01)
The aim of this study was to determine the cholecystokinin (CCK) receptor subtype involved in the direct myogenic effect of CCK on pig ileum. Smooth muscle cells were dispersed from pig ileum circular muscle layer and incubated in the presence
K Kitagawa et al.
Chemical & pharmaceutical bulletin, 49(8), 958-963 (2001-08-23)
Application of the fluoren-9-ylmethoxycarbonyl (Fmoc)-based solid-phase segment condensation approach to the preparation of sulfated peptides was investigated through the synthesis of human big gastrin-II, a 34-residue sulfated tyrosine [Tyr(SO3H)]-containing peptide. Highly acid-sensitive 2-chlorotrityl resin (Clt resin) was exclusively employed as
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