F5053

Flavin-Containing Monooxygenase-3, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution

• 동의어(들): FMO-3
• EC 번호: 1.14.13.8 (BRENDA, IUBMB)
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 재조합: expressed in baculovirus infected insect cells
• Quality Level: 200
• 양식: buffered aqueous solution
• 분자량: 55-60 kDa
• 포장: vial of 2.5 mg
• UniProt 수납 번호: P31513
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... FMO3(2328)

설명

일반 설명

Flavin-Containing Monooxygenase-3 (FMO3) is a member of the flavin-containing monooxygenase (FMO) family of enzymes. It is highly expressed in the human liver.

애플리케이션

FMO3 is the major human hepatic form.

생화학적/생리학적 작용

Flavin-Containing Monooxygenase-3 (FMO3) facilitates the oxidization of several drugs, chemicals, and xenobiotics. Human FMO3 is also involved in the synthesis of N-oxide of trimethylamine (TMAO) from trimethylamine (TMA). Mutations in the FMO3 gene are associated with trimethylaminuria or fish odor syndrome. Deficiency of the FMO3 gene results in lower plasma TMAO levels, which may reduce the risk of developing atherosclerosis and thrombosis.

물리적 형태

Solution in 100 mM potassium phosphate buffer, pH 7.4

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)