추천 제품
생물학적 소스
bovine neck ligament
Quality Level
양식
powder
UniProt 수납 번호
저장 온도
2-8°C
SMILES string
N1([C@@H](CCC1)C(=O)NC)C(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)[C@H](CC)C)C(C)C
InChI
1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1
InChI key
DPUYCSDGMSDKKV-MKBYFEBXSA-N
유전자 정보
cow ... ELN(280781)
애플리케이션
Elastin is a structural protein which has been used in studies of Chronic obstructive pulmonary disease (COPD). It may be used to investigate why there is a lack of repair for these proteins in patients with COPD.
Highly stable and hemocompatible protein now finding use in construction of biomaterials as a result of several strategies for its solubilization.
생화학적/생리학적 작용
Protein responsible for the elasticity of many tissues. It is especially important in blood vessels, where it comprises about 50% of the dry tissue weight.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
H M Morrison et al.
Biochimica et biophysica acta, 1430(2), 179-190 (1999-03-20)
Solubilization of elastin by human leukocyte elastase (HLE) cannot be analyzed by conventional kinetic methods because the biologically relevant substrate is insoluble and the concentration of enzyme-substrate complex has no physical meaning. We now report quantitative measurements of the binding
N Vyavahare et al.
The American journal of pathology, 155(3), 973-982 (1999-09-17)
Elastin, an abundant structural protein present in the arterial wall, is prone to calcification in a number of disease processes including porcine bioprosthetic heart valve calcification and atherosclerosis. The mechanisms of elastin calcification are not completely elucidated. In the present
Isabella C P Rodrigues et al.
Scientific reports, 12(1), 5230-5230 (2022-03-30)
Vascular graft surgeries are often conducted in trauma cases, which has increased the demand for scaffolds with good biocompatibility profiles. Biodegradable scaffolds resembling the extracellular matrix (ECM) of blood vessels are promising vascular graft materials. In the present study, polyurethane
Mervyn J Merrilees et al.
Respiratory research, 9, 41-41 (2008-05-20)
COPD is characterised by loss of alveolar elastic fibers and by lack of effective repair. Elastic fibers are assembled at cell surfaces by elastin binding protein (EBP), a molecular chaperone whose function can be reversibility inhibited by chondroitin sulphate of
Pro-inflammatory phenotype of COPD fibroblasts not compatible with repair in COPD lung.
Zhang J., et al.
Journal of Cellular and Molecular Medicine (2011)
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