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Merck
모든 사진(2)

주요 문서

C9426

Sigma-Aldrich

CHAPS hydrate

BioReagent, suitable for electrophoresis, ≥98% (HPLC)

동의어(들):

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate, CHAPS

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About This Item

실험식(Hill 표기법):
C32H58N2O7S · xH2O
CAS Number:
Molecular Weight:
614.88 (anhydrous basis)
MDL number:
UNSPSC 코드:
12161902
PubChem Substance ID:
NACRES:
NB.22

설명

zwitterionic

Quality Level

제품 라인

BioReagent

분석

≥98% (HPLC)

양식

powder

분자량

614.88 g/mol (anhydrous basis)

기술

electrophoresis: suitable
protein quantification: suitable

불순물

<0.04% DMF

mp

157 °C (dec.) (lit.)

solubility

water: 50 mg/mL, clear, colorless

적합성

suitable for electrophoresis

저장 온도

room temp

SMILES string

O.C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1

InChI key

SJCUTFKCLFLIFE-JWTJKVBLSA-N

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일반 설명

CHAPS is a non-denaturing, zwitterionic sulfobetaine detergent. It is mild and solubilizes membrane proteins and receptors. It is useful for breaking protein-protein interactions. It is a derivative of the naturally occurring bile salts. It has small micellar molecular weight (6,150) and high critical micellar concentration (6 - 10 mM) allowing it to be removed from samples by dialysis.

애플리케이션

CHAPS has been used:
  • For membrane permeabilization of cells
  • As a component in lysis buffer for homogenization of liver tissues as well as adipose tissue
  • As a component in denaturing buffer in enzyme characterization
  • As a component of 2D- sample buffer in 2D electrophoresis
  • For protein solubilization in isoelectric focusing

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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