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주요 문서

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C6239

Cinalukast

Name: Cinalukast
Brand: SIGMA

~98% (HPLC)

동의어(들):

(E)-4-[[3-(2-(4-Cyclobutyl-2-thiazolyl)ethenyl)phenyl]amino]-2,2-diethyl-4-oxobutanoic acid, Ro 24-5913

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About This Item

실험식(Hill 표기법):

C₂₃H₂₈N₂O₃S

CAS Number:

128312-51-6

Molecular Weight:

412.55

MDL number:

MFCD00864778

UNSPSC 코드:

12352202

PubChem Substance ID:

24724447

NACRES:

NA.77

추천 제품

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Sigma-Aldrich

SML1225

Indisulam

Sigma-Aldrich

G6423

Gemcitabine hydrochloride

Sigma-Aldrich

R8404

Rufinamide

Sigma-Aldrich

SML0094

Bikinin

Sigma-Aldrich

A7410

Amiloride hydrochloride hydrate

Sigma-Aldrich

901534

(S,R,S)-AHPC-C₆-CO₂H hydrochloride

Sigma-Aldrich

I7378

Indomethacin

Sigma-Aldrich

SML1532

Cinaciguat hydrochloride

S458104

QUININE DIHYDROCHLORIDE MONOHYDRATE

Sigma-Aldrich

L7260

Oleoyl-L-α-lysophosphatidic acid sodium salt

분석

~98% (HPLC)

Quality Level

100

양식

solid

색상

off-white

solubility

DMSO: >10 mg/mL
H₂O: insoluble

주관자

Roche

저장 온도

2-8°C

SMILES string

CCC(CC)(CC(=O)Nc1cccc(\C=C\c2nc(cs2)C3CCC3)c1)C(O)=O

InChI

1S/C23H28N2O3S/c1-3-23(4-2,22(27)28)14-20(26)24-18-10-5-7-16(13-18)11-12-21-25-19(15-29-21)17-8-6-9-17/h5,7,10-13,15,17H,3-4,6,8-9,14H2,1-2H3,(H,24,26)(H,27,28)/b12-11+

InChI key

BZMKNPGKXJAIDV-VAWYXSNFSA-N

유전자 정보

human ... CYSLTR1(10800)

생화학적/생리학적 작용

Specific CysLT1 leukotriene receptor antagonist.

특징 및 장점

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

083K4616

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Synergism exhibited by LTD4 and PAF receptor antagonists in decreasing antigen-induced airway microvascular leakage.

M A Wasserman et al.

Advances in prostaglandin, thromboxane, and leukotriene research, 23, 271-273 (1995-01-01)

Studies of the combination of Ro 24-5913, a peptidoleukotriene antagonist, and Ro 24-4736, a PAF antagonist, in guinea pig and rat models of lung inflammation.

A F Welton et al.

Annals of the New York Academy of Sciences, 744, 274-288 (1994-11-15)

Degradation profile and reversed-phase LC method development of the antiinflammatory drug, Ro 24-5913.

N D Aggarwal et al.

Journal of pharmaceutical and biomedical analysis, 11(10), 1037-1043 (1993-10-01)

Pharmacologic actions of Ro 24-5913, a novel antagonist of leukotriene D4.

M O'Donnell et al.

The Journal of pharmacology and experimental therapeutics, 259(2), 751-758 (1991-11-01)

Ro 24-5913, (E)-4-[3-[2-(4-cyclobutyl-2- thiazolyl)ethenyl]phenylamino]-2,2-diethyl-4-oxobutanoic acid, has been identified as a chemically unique, potent and selective LTD4 antagonist. In vitro, Ro 24-5913 competes with [3H]LTD4 for its binding site on guinea pig lung membranes with an IC50 of 6.4 +/- 2.2

Complexation study of cinalukast and montelukast with cyclodextrines.

I Durán Merás et al.

Journal of pharmaceutical and biomedical analysis, 43(3), 1025-1032 (2006-11-23)

A fluorimetric study on the spectral characteristics of two antileukotrienes, cinalukast and montelukast, has been performed. Ionization constants of both of them have been photometrically calculated. Cinalukast pK(a) in ethanol:water 50:50 (v/v) medium resulted to be 2.2+/-0.1. Because the spectral

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주요 문서

Cinalukast

~98% (HPLC)

About This Item

추천 제품

속성

분석

Quality Level

양식

색상

solubility

주관자

저장 온도

SMILES string

InChI

InChI key

유전자 정보

설명

생화학적/생리학적 작용

특징 및 장점

안전성 정보

Storage Class Code

WGK

Flash Point (°F)

Flash Point (°C)

개인 보호 장비

문서

시험 성적서(COA)

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