모든 사진(1)
About This Item
실험식(Hill 표기법):
C26H21N3O2
CAS Number:
Molecular Weight:
407.46
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.32
추천 제품
양식
solid
Quality Level
저장 온도
−20°C
SMILES string
Oc1ccc(cc1)C2=CN3C(=O)C(Cc4ccccc4)=NC3=C(Cc5ccccc5)N2
InChI
1S/C26H21N3O2/c30-21-13-11-20(12-14-21)24-17-29-25(22(27-24)15-18-7-3-1-4-8-18)28-23(26(29)31)16-19-9-5-2-6-10-19/h1-14,17,27,30H,15-16H2
InChI key
KAEGGIFPLJZUOZ-UHFFFAOYSA-N
일반 설명
Coelenterazine is an imidazopyrazinone derivative. It is a substrate for bioluminescence in many luminous marine organisms.
생화학적/생리학적 작용
10 times higher luminescence intensity than native coelenterazine.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
Coelenterazine-dependent luciferases
Markova S V and Vysotski E S
Biochemistry (Moscow), 80(6), 714-732 (2015)
Yifan Zhang et al.
Scientific reports, 7(1), 7195-7195 (2017-08-05)
Epilepsy is a chronic brain disorder characterized by recurrent seizures due to abnormal, excessive and synchronous neuronal activities in the brain. It affects approximately 65 million people worldwide, one third of which are still estimated to suffer from refractory seizures.
Eva A Naumann et al.
Nature neuroscience, 13(4), 513-520 (2010-03-23)
Existing techniques for monitoring neural activity in awake, freely behaving vertebrates are invasive and difficult to target to genetically identified neurons. We used bioluminescence to non-invasively monitor the activity of genetically specified neurons in freely behaving zebrafish. Transgenic fish with
Md Alamgir Hossain et al.
Cell reports, 29(7), 1934-1945 (2019-11-14)
To evade immunity, many viruses express interferon antagonists that target STAT transcription factors as a major component of pathogenesis. Because of a lack of direct structural data, these interfaces are poorly understood. We report the structural analysis of full-length STAT1
Péter Sok et al.
Structure (London, England : 1993), 28(10), 1101-1113 (2020-07-11)
Mitogen-activated protein kinases (MAPKs) control essential eukaryotic signaling pathways. While much has been learned about MAPK activation, much less is known about substrate recruitment and specificity. MAPK substrates may be other kinases that are crucial to promote a further diversification
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