B3412

Berberine hemisulfate salt

≥95%

• 동의어(들): Natural Yellow 18
• Linear Formula: C₂₀H₁₈NO₄ · 1/2SO₄
• CAS Number: 633-66-9
• Molecular Weight: 384.39
• 색상 지수 번호: 75160
• MDL number: MFCD00031743
• UNSPSC 코드: 12171500
• PubChem Substance ID: 24891718
• NACRES: NA.32

속성

• Quality Level: 100
• 분석: ≥95%
• 양식: powder
• solubility: methanol: soluble
• SMILES string: [O-]S([O-])(=O)=O.COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC.COc6ccc7cc8-c9cc%10OCOc%10cc9CC[n+]8cc7c6OC
• InChI: 1S/2C20H18NO4.H2O4S/c2*1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;1-5(2,3)4/h2*3-4,7-10H,5-6,11H2,1-2H3;(H2,1,2,3,4)/q2*+1;/p-2
• InChI key: OJVABJMSSDUECT-UHFFFAOYSA-L

설명

애플리케이션

Fluorescent stain for heparin in mast cells

생화학적/생리학적 작용

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves