추천 제품
생물학적 소스
goat
Quality Level
결합
biotin conjugate
항체 형태
affinity isolated antibody
항체 생산 유형
secondary antibodies
클론
polyclonal
양식
buffered aqueous solution
기술
direct ELISA: 1:20,000
저장 온도
2-8°C
타겟 번역 후 변형
unmodified
일반 설명
Human IgMs are the initial immunoglobulin isotypes that appear in blood in response to the first exposure to external antigens. IgMs have been implicated in CNS myelin repair and increased secretory IgM levels have been linked to rhino-conjunctivitis . Anti-Human IgM (μ-chain specific)-Biotin antibody is specific for human IgM and does not bind other human immunoglobulins.
IgM antibody is produced by B cells and plays a pivotal role in primary defence mechanism. The main function is to recognise and eliminate foreign invaders like bacteria and viruses, cellular waste as well as precancerous and cancerous lesions. Anti-human IgM (μ-chain specific) −biotin antibody can be used in micro ELISA to determine IgD isotype antibody to phosphorylcholine (PC) . Goat anti-human IgM antibodies react specifically with human IgM but not with other human immunoglobulins.
면역원
Purified human IgM
Purified human IgM.
애플리케이션
Anti-Human IgM (μ-chain specific)-Biotin antibody is suitable for use in ELISA (1:2000) .
물리적 형태
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
S D Litwin et al.
European journal of immunology, 17(4), 483-489 (1987-04-01)
As part of a broader analysis into the function of IgD, and especially into the role of human IgD-secreting cells, fresh human tonsil lymphocyte cultures were analyzed. The goals were to define the origins of "externalized" supernatant IgD and to
A Ripamonti et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(48), 12797-12802 (2017-11-15)
Follicular helper T cells (TFHs) are a key component of adaptive immune responses as they help antibody production by B cells. Differentiation and function of TFH cells are controlled by the master gene BCL6, but it is largely unclear how
Miguel A Trujillo et al.
DNA and cell biology, 22(8), 513-523 (2003-10-21)
We examined the role of BCR cell membrane redistribution in anti-IgM-induced apoptosis in three human B cell lines, RA#1, 2G6, and MC116, that differ in their relative levels of sIgM expression. The apoptotic response was found to be dependent on
S D Litwin et al.
Clinical and experimental immunology, 80(2), 263-267 (1990-05-01)
The participation of human IgD class antibody in local immune responses of breast tissue was studied by analysing the sera-to-milk ratios of total IgD, IgM, IgA, IgG isotypes and albumin found in matched samples, and by analysing the sera-to-milk (S/M)
Marta Vidal et al.
Journal of immunological methods, 455, 41-54 (2018-02-06)
Quantitative suspension arrays are powerful immunoassays to measure antibodies against multiple antigens in large numbers of samples in a short time and using few microliters. To identify antigen targets of immunity for vaccine development against complex microbes like Plasmodium falciparum
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