A9227

ABT-491 hydrochloride

≥98% (HPLC)

• 동의어(들): 4-Ethynyl-N,N-dimethyl-3-[3-fluoro-4-[(2-methyl-1H-imidazo-[4,5-c]pyridin-1-yl)methyl]benzoyl]-1H-indole-1-carboxamide hydrochloride, A-137491
• 실험식(Hill 표기법): C₂₈H₂₂N₅O₂F · HCl
• CAS Number: 189689-94-9
• Molecular Weight: 515.97
• MDL number: MFCD00945301
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24724404
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 저장 조건: desiccated
• 색상: white to beige
• mp: 170-178 °C (lit.)
• solubility: H₂O: freely soluble 22 mg/mL
• 주관자: Abbott
• 저장 온도: 2-8°C
• SMILES string: Cl[H].CN(C)C(=O)n1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc34)c(F)c2)c5c(cccc15)C#C
• InChI: 1S/C28H22FN5O2.ClH/c1-5-18-7-6-8-25-26(18)21(16-34(25)28(36)32(3)4)27(35)19-9-10-20(22(29)13-19)15-33-17(2)31-23-14-30-12-11-24(23)33;/h1,6-14,16H,15H2,2-4H3;1H
• InChI key: AWRGBOKANQBIBM-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Highly potent, selective and orally active platelet-activating factor (PAF) receptor antagonist. K_i = 0.6 nM in human platelets.

특징 및 장점

This compound is featured on the PAF Receptor page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)