A6671

Actinonin

≥98% (TLC), powder, leucine aminopeptidase inhibitor

• 동의어(들): 3-[[1-[(2-(Hydroxymethyl)-1-pyrrolidinyl)carbonyl]-2-methylpropyl]carbamoyl]octanohydroxamic acid
• 실험식(Hill 표기법): C₁₉H₃₅N₃O₅
• CAS Number: 13434-13-4
• Molecular Weight: 385.50
• Beilstein: 1555250
• MDL number: MFCD00080257
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278232
• NACRES: NA.77

속성

• 제품명: Actinonin,
• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• 분석: ≥98% (TLC)
• 양식: powder
• solubility: ethanol: 50 mg/mL, clear, colorless
• 항생제 활성 스펙트럼: Gram-negative bacteria; Gram-positive bacteria
• 동작 모드: enzyme | inhibits
• 저장 온도: −20°C
• SMILES string: CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO
• InChI: 1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)
• InChI key: XJLATMLVMSFZBN-UHFFFAOYSA-N
• 유전자 정보: human ... ANPEP(290) , DPP4(1803) , ECE1(1889) , LAP3(51056)

설명

일반 설명

Chemical structure: peptide

애플리케이션

Actinonin has been used as a control to inhibit meprin-β activity in C57BL/6 mice. It has also been used to study the high-affinity interaction of EcPDF with actinonin by 15N NMR spectroscopy and isothermal titration.

생화학적/생리학적 작용

Actinonin has inhibitory action against peptide deformylase (PDF). It is effective against Gram-positive and fastidious Gram-negative microorganisms.

Actinonin is an inhibitor of leucine aminopeptidase. Actinonin has also been used to improve antibacterial activity and antiobesity therapeutics.

특징 및 장점

This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)