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Merck
모든 사진(1)

주요 문서

A0793

Sigma-Aldrich

Anti-Dog IgG (whole molecule)–Alkaline Phosphatase antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

동의어(들):

Rabbit Anti-Dog IgG (whole molecule)–AP

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

alkaline phosphatase conjugate

항체 형태

IgG fraction of antiserum

항체 생산 유형

secondary antibodies

클론

polyclonal

양식

buffered aqueous solution

종 반응성

dog

기술

direct ELISA: 1:6,000
dot blot: 1:4,000
western blot (chemiluminescent): 1:4,000

배송 상태

wet ice

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

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일반 설명

An immunoglobulin has two heavy chain and two light chain connected by disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. In dogs four subclasses of IgG (IgG1 -IgG4) are present.
Dog IgGs are glycoprotein antibodies that regulate several immunological responses. Canine IgGs can be used as markers for detecting immune-mediated haemolytic anaemia, adverse food reactions and also for assessing the risk of L. infantum transmission in dogs.

특이성

Anti-Dog IgG (whole molecule) antibody is specific for IgG in dogs when tested against normal dog serum and dog IgG by double-diffusion and immunoelectrophoretic assays prior to conjugation.

면역원

IgG isolated from pooled normal dog serum

애플리케이션

Anti-Dog IgG (whole molecule)−Alkaline Phosphatase antibody produced in rabbit has been used in enzyme-linked immunosorbent assay (ELISA), and immunoblotting.

생화학적/생리학적 작용

Immunoglobulin G (IgG) participates in hypersensitivity type II and type III.

물리적 형태

Solution in 0.05 M Tris, pH 8.0, containing 1% bovine serum albumin, 1 mM MgCl2 and 15 mM sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Susan C Barsoum et al.
The Journal of laboratory and clinical medicine, 142(6), 399-413 (2004-01-10)
An alternative approach to somatic gene therapy is to deliver a therapeutic protein by implanting "universal" recombinant cells that are immunologically protected from graft rejection with alginate microcapsules. This strategy has proved successful in reversing pathologic conditions in several rodent
Molecular Genetics of Immunoglobulin, 17 (1987)
The Immunoglobulins: Structure and Function (2011)
A Bead-Based Flow Cytometric Assay for Monitoring Yersinia pestis Exposure in Wildlife
Chandler JC, et al.
Journal of Clinical Microbiology, 56(7) (2018)
Michaela Vlkova et al.
PLoS neglected tropical diseases, 5(10), e1344-e1344 (2011-10-25)
Phlebotomine sand flies are blood-sucking insects that can transmit Leishmania parasites. Hosts bitten by sand flies develop an immune response against sand fly salivary antigens. Specific anti-saliva IgG indicate the exposure to the vector and may also help to estimate

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