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일반 설명
MDP (Methylenediphosphonic acid) is a phosphonic analog of ATP.
애플리케이션
Suitable for
- preparation of analogs of natural di- and tri-phosphates
- mass spectrometry studies as analytical standard
- molecular studies related to inflammation
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
이미 열람한 고객
J.A. Stock
The Journal of Organic Chemistry, 44, 3997-3997 (1979)
T G Rudd et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 18(9), 872-876 (1977-09-01)
The biologic and imaging characteristics of Tc-99m MDP and Tc-99m PPi were compared in animals and patients using freeze-dried bone-imaging kits. Biodistribution data in rabbits showed Tc-99m MDP had slightly higher bone uptake, significantly lower blood levels, and faster urinary
Phosphonic acid analogs of nucleoside phosphates. I. The synthesis of 5'-adenylyl methylenediphosphonate, a phosphonic acid analog of ATP
Myers TC et al
Journal of the American Chemical Society, 85, 3292-3295 (1963)
R. Engel
Chemical Reviews, 77, 349-349 (1977)
H F Kung et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 19(9), 1027-1031 (1978-09-01)
Bidentate monophosphates--phosphonoacetate (PAA), 2-phosphonoproprionate (PPA), 2-methyl-2-phosphonoproprionate (MPPA), and carbamyl phosphate (CAP)--which are pyrophosphate analogs, were successfully labeled with Sn(II)-reduced [99mTc] pertechnetate in high yield (greater than 95%). Biodistribution studies show that these Tc-99m-labeled monophosphates do localize in bone. At 2
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