추천 제품
생물학적 소스
Bacillus brevis
Quality Level
분석
~90% (HPLC)
양식
powder
불순물
≤5% water
색상
white to off-white
항생제 활성 스펙트럼
Gram-negative bacteria
Gram-positive bacteria
동작 모드
cell membrane | interferes
enzyme | inhibits
저장 온도
2-8°C
SMILES string
CC(C)C[C@@H]1NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]4CCCN4C(=O)[C@@H](Cc5ccccc5)NC1=O)C(C)C)C(C)C
InChI key
IUAYMJGZBVDSGL-JYFSIOBESA-N
일반 설명
Chemical structure: peptide
애플리케이션
Gramicidin is a naturally occuring polypeptide antibiotic. It functions as a transmembrane ion channel and is used for studies on phospholipid bilayer membrane fluidity measured by lateral diffusion.
생화학적/생리학적 작용
Gramicidin′s bactericidal activity is a result of increasing the permeability of the bacterial cell membrane. This allows inorganic monovalent cations to travel through unrestricted which thereby destroys the ion gradient between the cytoplasm and the extracellular environment .
Naturally occuring polypeptide antibiotic with Tyr at position 11; functions as a transmembrane ion channel.
포장
10mg
기타 정보
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place. Keep in a dry place.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
G.A. Brewer
Anal. Profiles Drug Subst., 8, 179-179 (1979)
Dong Hyeon Lee et al.
Yonsei medical journal, 49(3), 459-471 (2008-06-27)
This study examined the expression and function of inward rectifier K(+) channels in cultured rat hepatic stellate cells (HSC). The expression of inward rectifier K(+) channels was measured using real-time RT-PCR, and electrophysiological properties were determined using the gramicidin-perforated patch-clamp
Physiology and Pathology of Chloride Transporters and Channels in the Nervous System: From Molecules to Diseases.
Francisco J. Alvarez-Leefmans; Eric Delpire
Physiology and Pathology of Chloride Transporters and Channels in the Nervous System: From Molecules to Diseases, 142-142 (2009)
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