29311

CHES

BioUltra, ≥99.5% (T)

• 동의어(들): 2-(Cyclohexylamino)ethanesulfonic acid
• 실험식(Hill 표기법): C₈H₁₇NO₃S
• CAS Number: 103-47-9
• Molecular Weight: 207.29
• Beilstein: 2967601
• EC Number: 203-115-6
• MDL number: MFCD00003835
• UNSPSC 코드: 12161700
• PubChem Substance ID: 57648360
• NACRES: NA.25

속성

• 제품 라인: BioUltra
• Quality Level: 200
• 분석: ≥99.5% (T)
• 양식: powder
• 불순물: insoluble matter, passes filter test
• 무기 잔류물: ≤0.05%
• 손실: ≤0.5% loss on drying, 110 °C
• pH: 3.0-5.0 (25 °C, 0.5 M in H₂O)
• 유용한 pH 범위: 8.6-10.0
• pKa(25 °C): 9.3
• solubility: H₂O: 0.5 M at 20 °C, clear, colorless
• 음이온 미량물: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤500 mg/kg
• 양이온 미량물: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 0.5 M in H₂O
• UV 흡수: λ: 260 nm A_max: 0.08; λ: 280 nm A_max: 0.05
• SMILES string: OS(=O)(=O)CCNC1CCCCC1
• InChI: 1S/C8H17NO3S/c10-13(11,12)7-6-9-8-4-2-1-3-5-8/h8-9H,1-7H2,(H,10,11,12)
• InChI key: MKWKNSIESPFAQN-UHFFFAOYSA-N

설명

일반 설명

Cyclohexylaminoethanesulfonic acid (CHES) is a buffering agent. Its structure contains a hydrophilic taurine (2-aminoethanesulfonic acid) moiety and a hydrophobic cyclohexyl group. CHES binds to the active site of several enzymes and inhibits substrate binding and enzymatic activity. Therefore, CHES may be used as a scaffold for new drug development for regulating enzyme activity.

애플리케이션

2-(Cyclohexylamino)ethanesulfonic acid (CHES) has been used in the preparation of dimethyl trisulfide- polysorbate 80 (DMTS-PS80) formulation.

기타 정보

Buffer for studying pH-dependent processes in enzymology;citation Has a high affinity for the iodoacetate binding site of liver alcohol dehydrogenase.citation

Buffer for studying pH-dependent processes in enzymology; Has a high affinity for the iodoacetate binding site of liver alcohol dehydrogenase.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves