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Merck
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주요 문서

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27042

Sigma-Aldrich

Chondroitin 4-sulfate sodium salt from bovine trachea

mixture of isomers, main component: chondroitin 4-sulfate

동의어(들):

CSA, Chondroitin sulfate A sodium salt

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About This Item

CAS Number:
39455-18-0
MDL number:
MFCD00130792
UNSPSC 코드:
12352201
NACRES:
NA.25

생물학적 소스

bovine trachea

Quality Level

200

양식

powder

광학 활성

[α]20/D −25±5°, c = 1% in H2O

불순물

≤10% water

solubility

H2O: 0.1 g/mL, clear to slightly turbid, colorless to light yellow

저장 온도

2-8°C

SMILES string

CC1=C(CCN2CCC(\CC2)=C(/c3ccccc3)c4ccc(F)cc4)C(=O)N5C=CSC5=N1

애플리케이션

Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans.

기타 정보

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
STBJ0943
STBH5273
STBG4578V
STBF7435V
STBC4286V

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문서 라이브러리 방문

Tomomi Izumikawa et al.
Biochimica et biophysica acta, 1830(10), 4806-4812 (2013-07-03)
Previously, we identified two missense mutations in the chondroitin N-acetylgalactosaminyltransferase-1 gene in patients with neuropathy. These mutations are associated with a profound decrease in chondroitin N-acetylgalactosaminyltransferase-1 enzyme activity. Here, we describe a patient with neuropathy who is heterozygous for a
Gunnar Dick et al.
The Journal of biological chemistry, 288(38), 27384-27395 (2013-08-14)
Chondroitin sulfate (CS) and the CS-rich extracellular matrix structures called perineuronal nets (PNNs) restrict plasticity and regeneration in the CNS. Plasticity is enhanced by chondroitinase ABC treatment that removes CS from its core protein in the chondroitin sulfate proteoglycans or
Tadahisa Mikami et al.
Biochimica et biophysica acta, 1830(10), 4719-4733 (2013-06-19)
Chondroitin sulfate proteoglycans (CSPGs) are principal pericellular and extracellular components that form regulatory milieu involving numerous biological and pathophysiological phenomena. Diverse functions of CSPGs can be mainly attributed to structural variability of their polysaccharide moieties, chondroitin sulfate glycosaminoglycans (CS-GAG). Comprehensive
Clare M Galtrey et al.
Brain research reviews, 54(1), 1-18 (2007-01-16)
Chondroitin sulfate proteoglycans (CSPGs) consist of a core protein and glycosaminoglycan (GAG) chains. There is enormous structural diversity among CSPGs due to variation in the core protein, the number of GAG chains and the extent and position of sulfation. Most
Juliette Sage et al.
Biochemistry, 52(37), 6487-6498 (2013-08-24)
Human cysteine cathepsin S (catS) participates in distinct physiological and pathophysiological cellular processes and is considered as a valuable therapeutic target in autoimmune diseases, cancer, atherosclerosis, and asthma. We evaluated the capacity of negatively charged glycosaminoglycans (heparin, heparan sulfate, chondroitin
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