366927

Chloroform

suitable for HPLC, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

• 동의어(들): Methylidyne trichloride, Trichloromethane
• 실험식(Hill 표기법): CHCl₃
• CAS Number: 67-66-3
• Molecular Weight: 119.38
• Beilstein: 1731042
• MDL number: MFCD00000826
• UNSPSC 코드: 12190000
• PubChem Substance ID: 329755457
• NACRES: NA.04
• bp: 60.5-61.5 °C (lit.)
• vapor pressure: 160 mmHg ( 20 °C)

속성

• Grade: HPLC grade
• Quality Level: 100
• vapor density: 4.1 (vs air)
• vapor pressure: 160 mmHg ( 20 °C)
• 분석: ≥99.8%
• 양식: liquid
• 정제법: glass distillation
• 포함: 0.5-1.0% ethanol as stabilizer
• 기술: HPLC: suitable
• 불순물: Acetone and aldehyde, passes test; Acid and chloride, passes test; Free chlorine (Cl), passes test; H₂SO₄, passes test (darkened); ≤0.01% water
• 증발 잔류물: <0.0003%
• 색상: APHA: ≤10
• refractive index: n20/D 1.445 (lit.)
• bp: 60.5-61.5 °C (lit.)
• mp: −63 °C (lit.)
• density: 1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.)
• 양이온 미량물: Pb: ≤0.05 ppm
• λ: H₂O reference
• UV 흡수: λ: 245 nm A_max: 1.00; λ: 255 nm A_max: 0.15; λ: 260 nm A_max: 0.15; λ: 270 nm A_max: 0.02; λ: 290 nm A_max: 0.01; λ: 400 nm A_max: 0.01
• 적합성: passes test for HPLC
• 저장 온도: room temp
• SMILES string: ClC(Cl)Cl
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• InChI key: HEDRZPFGACZZDS-UHFFFAOYSA-N

설명

애플리케이션

• Novel Approaches for the Analysis and Isolation of Benzylisoquinoline Alkaloids in Chelidonium majus.: This study presents innovative methodologies using chloroform in the extraction and analysis processes, highlighting advances in alkaloid chemistry (Ganzera et al., 2024).


• Antioxidant, anti-amylase, anti-lipase, and efficiency of Satureja fatty acid on the anti-inflammatory parameters in lipopolysaccharide-stimulated macrophage through Nrf2/NF-kB/NADH oxidase pathway.: Although primarily focused on biological assays, this paper includes essential methodologies employing chloroform for the extraction and purification of biochemical compounds (Saharkhiz MJ et al., 2024).


• Recent additions and access to a multidimensional lipidomic database containing liquid chromatography, ion mobility spectrometry, and tandem mass spectrometry information.: Chloroform is utilized as a key solvent in the extraction and analysis processes within lipidomics, demonstrating its critical role in modern analytical techniques (Baker ES et al., 2024).


• Preparation and optimization of dummy molecularly imprinted polymer-based solid-phase extraction system for selective enrichment of p-toluene sulfonate esters genotoxic impurities.: The study includes the use of chloroform in the preparation of polymers for advanced chromatographic applications, illustrating its versatility in analytical methodologies (Shan G et al., 2024).

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안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H319,H331,H336,H351,H361d,H372
• 예방조치 성명서: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• 표적 기관: Central nervous system, Liver,Kidney
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point (°F): does not flash
• Flash Point (°C): does not flash