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일반 설명
Hydrogen chloride solution contains 4.0 M hydrogen chloride in 1,4-dioxane as the solvent. It is commonly used as a deprotection reagent during the deprotection of the tert-butoxycarbonyl (Boc) group of various amino acids and peptides. Additionally, it serves as a reagent in various organic synthesis reactions, including the synthesis of N-9-Fluorenylmethoxycarbonyl- (Fmoc) amino-acid chlorides.
애플리케이션
Hydrogen chloride solution (4.0 M in dioxane) can be used as:
- A reagent for the deprotection of the N-Boc protecting group from various heterocyclic derivatives.
- A reagent for the deprotection of polymer protecting groups. For instance, deprotection of benzyl ether-protected polymer.
- A polymerization initiator in combination with ZnCl2 in the synthesis of formyl terminated poly(ethyl vinyl ether) from ethyl vinyl ether (EVE).
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - Met. Corr. 1 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
보충제 위험성
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point (°F)
62.6 °F - closed cup
Flash Point (°C)
17 °C - closed cup
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