SMB01383

PhIP

≥95% (HPLC)

• 동의어(들): 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
• 실험식(Hill 표기법): C₁₃H₁₂N₄
• CAS Number: 105650-23-5
• Molecular Weight: 224.26
• MDL number: MFCD00210745
• UNSPSC 코드: 12352100
• NACRES: NA.28

속성

• 생물학적 소스: synthetic
• Quality Level: 200
• 분석: ≥95% (HPLC)
• 양식: solid
• 배송 상태: 2-8°C
• 저장 온도: 2-8°C
• SMILES string: NC1=NC2=NC=C(C3=CC=CC=C3)C=C2N1C
• InChI: 1S/C13H12N4/c1-17-11-7-10(9-5-3-2-4-6-9)8-15-12(11)16-13(17)14/h2-8H,1H3,(H2,14,15,16)
• InChI key: UQVKZNNCIHJZLS-UHFFFAOYSA-N

설명

일반 설명

PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) is a dietary genotoxic carcinogen formed in heat processed meat and fish via the Maillard reaction. PhIP is a primary metabolite activated by CYP1A2 and N-acetyltransferase 1 or sulfotransferase to DNA reactive metabolite.

생화학적/생리학적 작용

Carcinogen developed in grilled meats. Induces breast and colon cancer in rats.

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H301,H315,H319,H335,H351
• 예방조치 성명서: P202 - P261 - P264 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable