N4126

Nicotinic acid

≥98%

• 동의어(들): 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid, Vitamin B₃
• 실험식(Hill 표기법): C₆H₅NO₂
• CAS Number: 59-67-6
• Molecular Weight: 123.11
• Beilstein: 109591
• EC Number: 200-441-0
• MDL number: MFCD00006391
• UNSPSC 코드: 12352106
• PubChem Substance ID: 24897668
• NACRES: NA.25

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• 분석: ≥98%
• 양식: powder
• 색상: white to off-white
• mp: 236-239 °C (lit.)
• SMILES string: OC(=O)c1cccnc1
• InChI: 1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
• InChI key: PVNIIMVLHYAWGP-UHFFFAOYSA-N
• 유전자 정보: human ... CYP1A2(1544) ; rat ... Chrnb2(54239)

설명

일반 설명

Nicotinic acid is also known as vitamin B₃ or Niacin. It is a water soluble vitamin. Niacin can be either synthesized within the body or can be obtained from dietary sources.

애플리케이션

Nicotinic acid has been used:

• as a component of the MS vitamins stock solution
• for the detection of siderophores in Escherichia coli bacterial culture
• as a component of the holidic medium for adult Drosophila .

생화학적/생리학적 작용

Niacin is involved in the production of nicotinamide adenine dinucleotide (NAD⁺), which is used in the adenine triphosphate (ATP) production in mitochondrial oxidative phosphorylation. It also decreases hepatic production of very-low density lipoproteins (VLDL), and apolipoprotein B (apo-B). Niacin deficiency leads to pellagra.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): 379.4 °F - closed cup
• Flash Point (°C): 193 °C - closed cup
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves