07858

(R)-(−)-3-Amino-1-Boc-piperidine

≥98.0% (TLC)

• 동의어(들): (R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate
• 실험식(Hill 표기법): C₁₀H₂₀N₂O₂
• CAS Number: 188111-79-7
• Molecular Weight: 200.28
• MDL number: MFCD03094717
• UNSPSC 코드: 12352005
• PubChem Substance ID: 329748523
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥98.0% (TLC)
• 광학 활성: [α]/D -28.5±2°, c = 1 in DMF
• SMILES string: CC(C)(C)OC(=O)N1CCC[C@@H](N)C1
• InChI: 1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
• InChI key: AKQXKEBCONUWCL-MRVPVSSYSA-N

설명

일반 설명

(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.

애플리케이션

(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H319,H335
• 예방조치 성명서: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter